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1270 items
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... immediately after freeze-drying and after one month of storage. For lyophilization-2, samples were frozen at -50 "C for 3 h and then primary dried at -45 "C and 0.2 mbar for 21 h, which was followed by secondary drying at 20 *C for 30 h in a Telstar LyoBeta Mini freeze dryer (Spain). Vials were ...
... was not significantly increased (P=0.997 and 0.951 for T+M 1 + 1, after one and three months, respectively; P = 0.260 and 0.937 for T+M 3 + 2, after one and three months, respectively), except for the formulation with trehalose alone, for which an additional increase of approximately 20 nm was ...
... Lyophilization Lyophilization was performed under two «conditions. For lyophilization-1, samples were frozen at -80 "C for 3 h and then freeze- dried in a Beta 1–8 K freeze dryer (Martin Christ, Osterode am Harz, Germany) for 24 h, with primary drying at -10 "C and 0.340 mbar and secondary drying ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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Clockwise vertical-axis rotation in the West Vardar zone of Serbia: Tectonic implications
The Vardar-Tethyan mega-suture between the Eurasian and Adria (Gondwana) margins comprises remnants of oceanic lithosphere of Neotethys and distal parts of the adjacent continental margins including unconformable Late Cretaceous sedimentary cover and Cenozoic igneous rocks of post-obduction age. This study provides kinematic constraints for displacements and rotations affecting the Serbian part of the West Vardar and Jadar-Kopaonik units after the closure of the Neotethyan (= Sava) Ocean. The targets of the paleomagnetic research were Late Cretaceous sediments representing an ...... Complex, D— Danubicum. Age constraints for the rotations are as follows: post- Early Miocene for area 1 (this study); post-Oligocene for area 2 (this study); post-Oligocene to pre-Middle Miocene for area FG a; post- Middle Miocene to pre-Pliocene for area FG b (data for FG are from Lesić et al. 2007 and ...
... composition. The AMS was measured for all sites. The degree of anisotropy varied between 1.014 and 1.046 for most of them, higher values were only observed for sites 12 and 16 (1.095 and 1.125, respectively). The orientations of the principal susceptibility axes are random for sites 9–12 and 15. Concerning ...
... than that for the Rudnik Mts. area. Inclination flattening due to magnetic anisotropy could account for the flattening in the granodi- orites (AMS degree varies between 1.06–1.61 for the localities yielding statistically well-defined paleomagnetic Table 4 The overall mean directions for the Cretaceous ...Vesna Lesić, Emo Márton, Violeta Gajić, Dragana Jovanović, Vesna Cvetkov. "Clockwise vertical-axis rotation in the West Vardar zone of Serbia: Tectonic implications" in Swiss Journal of Geosciences, Basel : Springer International Publishing (2018). https://doi.org/10.1007/s00015-018-0321-8
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Ventex: an expert system for mine ventilation systems analysis
roblems relating to mine ventilation systems analysis are usually of a very complex nature. They involve the estimation of numerous interdependent parameters pertaining to the network status, ventilation status, ventilation system stability, air current losses, climate conditions, gas state, fire risk and dangerous dust pollution risk. The solution to these problems relies, to a great extent, on numerical methods. With the development of computer technology these methods were incorporated as numerical routes in software packages, such as the mine ...Nikola Lilić, Ranka Stanković, Ivan Obradović. "Ventex: an expert system for mine ventilation systems analysis" in Mining Technology, United Kingdom (1997)
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Synthesis of MnCo2O4 nanoparticles as modifiers for simultaneous determination of Pb(II) and Cd(II)
The porous spinel oxide nanoparticles, MnCo2O4, were synthesized by citrate gel combustion technique. Morphology, crystallinity and Co/Mn content of modified electrode was characterized and determined by Fourier transform infra-red spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive spectrometry (EDS), X-ray diffraction pattern analysis (XRD), simultaneous thermogravimetry and differential thermal analysis (TG/DTA). Nanoparticles were used for modification of glassy carbon electrode (GCE) and new sensor was applied for simultaneous determination of Pb(II) and Cd(II) ions in water samples with the ...Vesna Antunović, Marija Ilić, Rada Baošić, Dijana Jelić, Aleksandar Lolić. "Synthesis of MnCo2O4 nanoparticles as modifiers for simultaneous determination of Pb(II) and Cd(II)" in PLOS ONE (2019). https://doi.org/10.1371/journal.pone.0210904
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Application of the Fuzzy Model in the Evaluation and Selection of Hydraulic Excavators on Open-Pit Lignite Mine
Stevan Đenadić, Miloš Tanasijević, Vladimir Milisavljević, Dragan Ignjatović, Predrag Jovančić (2021)The production of lignite in large open-pit mines is mainly performed with continuously operating equipment, where bucket-wheel excavators, bucket-chain excavators, belt conveyors, and spreaders are the basic machines. Smaller machines, usually of discontinuous operating nature, are commonly categorized as auxiliary machines. This paper presents the research related to the analysis of auxiliary machine parameters with the case study for a hydraulic excavator. The purpose of the analysis was to develop a model of rating quality of service of the ...Stevan Đenadić, Miloš Tanasijević, Vladimir Milisavljević, Dragan Ignjatović, Predrag Jovančić. "Application of the Fuzzy Model in the Evaluation and Selection of Hydraulic Excavators on Open-Pit Lignite Mine" in SSRN Electronic Journal, Elsevier BV (2021). https://doi.org/10.2139/ssrn.3945617
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Natural two-dimensional pyrophyllite: Nanoscale lubricant, electrical insulator and easily-machinable material
Borislav Vasić, Radoš Gajić, Ivana Milošević, Žarko Medić, Marina Blagojev, Marko Opačić, Aleksandar Kremenović, Dejan Lazić (2022)Pyrophyllite, with the chemical formula Al2Si4O10(OH)2, is a naturally occurring and abundant van der Waals mineral belonging to the group of phyllosilicates. It is very soft, layered crystal used for sculpting and an excellent electrical and thermal insulator aimed for the operation at high pressure and temperature. Here, for the first time, two-dimensional (2D) pyrophyllite obtained by both mechanical and liquid phase exfoliation is presented and investigated at the nanoscale. The layered structure provides low friction coefficient of around ...Atomic force microscopy, Insulating properties, Nanofriction and wear, Natural two dimensional materials, Phyllosilicates, PyrophylliteBorislav Vasić, Radoš Gajić, Ivana Milošević, Žarko Medić, Marina Blagojev, Marko Opačić, Aleksandar Kremenović, Dejan Lazić. "Natural two-dimensional pyrophyllite: Nanoscale lubricant, electrical insulator and easily-machinable material" in Applied Surface Science, Elsevier BV (2022). https://doi.org/10.1016/j.apsusc.2022.155114
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The external aggregation Newton's method for solving nonlinear equations and applications
Marija Paunović, Dejan Ćebić, Nebojša Ralević. "The external aggregation Newton's method for solving nonlinear equations and applications" in The University Thought - Publication in Natural Sciences, Centre for Evaluation in Education and Science (CEON/CEES) (2020). https://doi.org/10.5937/univtho10-24982
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Overwiew of In-Pit Crushing & Conveying Technology in Open Pit Mines
The conditions under which contemporary surface mining operations is carried out obviously becoming increasingly complex. In such complex conditions, the optimization of haulage systems as the technological phase with the largest share in the total operating costs, is very important from the aspect of achieving profitability of the mining project. In a large number of cases, the application of traditional haulage systems with trucks (as the most dominant type of haulage in open pit mines) does not lead to ...Ali Nasirinezhad, Dejan Stevanović, Dragan Ignjatović, Petar Marković. "Overwiew of In-Pit Crushing & Conveying Technology in Open Pit Mines" in 8th International Conference MIining And Environmental Protection, Sokobanja, 22-25 September 2021, University of Belgrade, Faculty of Mining and Geology, Belgrade, Serbia (2021)
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Arsenic in tape waters of the south Pannonian basin (Serbia) and arsenic risk assessment
Petar Papić, Marina Ćuk, Maja Todorović, Jana Stojković, Bojan Hajdin, Nebojša Atanacković, Dušan Polomčić (2012)... 15% of the total, is used for drinking water supply in rural settle- ments. More than 600,000 inhabitants of Banat and Bačka (or about 40% of the population of Vojvodina) are exposed to drinking water whose arsenic and ammonia concentra- tions exceed drinking water standards. Arsenic concentra- tions ...
... • to a depth of 250 m, which meet drinking water standards. Depths below 250 m exhibited elevated total mineralization [19]. Arsenic Risk Assessment by the Drinking Water Pathway The end result of the assessment of groundwaters used for drinking water supply in the South Pannonian Basin should ...
... M. L., MOORE L., HAQUE R., STEINMAUS C., CHUNG J., HERNANDEZ A., LOP- IPERO P, Cancer Risk from Arsenic in Drinking Water. Implications for Drinking Water Standards, Elsevier Science, pp. 191-199, 1999. 40. UJEVIĆ BOŠNJAK M., CAPAK K., JAZBEC A., CASIOT C., SIPOS L., POLJAK V., DADIĆ Ž., Hydrochemical ...Petar Papić, Marina Ćuk, Maja Todorović, Jana Stojković, Bojan Hajdin, Nebojša Atanacković, Dušan Polomčić. "Arsenic in tape waters of the south Pannonian basin (Serbia) and arsenic risk assessment" in Polish Journal of Enivronmental Studies 21 no. 6, Olsztyn, Poland : Polish Journal of Enivronmental Studies (2012): 1783-1790
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Laboratory testing of fly ash
Fly ash is one of the most common waste materials created by burning of coal. It is composed of smaller particles, consisting mainly of aluminosilicate glass, mullite and quartz, which are collected by electrostatic separators (filter) of gaseous products arising from the combustion of coal. This paper presents the pozzolanic properties, mechanical properties, chemical and mineral composition of fly ash obtained in the combustion process in a power plant Nikola Tesla A (PPNT A) with the addition of a ...chemical composition, fly ash, mechanical properties, mineral properties, pozzolanic properties, X-ray diffraction... n was obtained by testing samples in accordance with the standards SRPS B.H8.359 369 [4-14] – Methods of test for coal and coke - Determination of the chemical composition of the ash, the basic provisions, and other related standards for the determination of some oxides that are provided standard ...
... was tested in laboratory for concrete and binders in "Highway Institute A. D.". Chemical analysis was performed on samples with volume of 10 g for "Series 1" (S1) and 10 g for "Series 2" (S2). In period from 1983 to 2004, testing of chemical composition was done for 59 samples and results are ...
... All prepared samples were stored for a while before the failure. The test was performed with three different series of samples: - samples cured in a wet chamber for 7 days, - samples cured in a wet chamber for 28 days, - samples cured in a wet chamber for 112 days. The uniaxila strength is ...Miloš Šešlija, Aleksandra Rosić, Nebojša Radović, Milinko Vasić, Mitar Đogo, Milovan Jotić. "Laboratory testing of fly ash" in Tehnički vijesnik (2016). https://doi.org/10.17559/TV-20150317171035
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Groundwater resources for drinking water supply in Serbia´s Southeast Pannonian basin
Dušan Polomčić, Bojan Hajdin, Marina Ćuk, Petar Papić, Zoran Stevanović. "Groundwater resources for drinking water supply in Serbia´s Southeast Pannonian basin" in Carpathian Journal of Earth and Environmental Sciences (2014)
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Actual contamination of the Danube and Sava rivers at Belgrade (2013)
Milan Antonijević, Marija Arsović, Josef Cáslavský, Vesna Cvetković, Predrag Dabić, Mladen Franko, Gordana Ilić, Milena Ivanovic, Nevena Ivanović, Milica Kosovac, Dragana Medić, Slobodan Najdanović, Milica Nikolić, Jovana Novaković, Tatjana Radovanović, Djurdjina Ranić, Bojan Šajatović, Gorica Špijunović, Ivana Stankov, Jelena Tošović, Polonca Trebse, Olivera Vasiljević, Jan Schwarzbauer (2014)rečni sistemi, stanje zagađenja, organski zagađivači, teški metali, skrining analize, non-target screening... acid; the flow rate was 1 mL min-1 and the wavelength for thiamethoxam was 247 nm, for imidacloprid 250 nm and for clothianidin 260 nm. The retention time for thiamethoxam was 5.7 min, for imidacloprid 8.5 min and for clothianidin 7.4 min. For quantification purposes, calibration curves in the range ...
... on the state of pollution but might also act as a base for further well adapted monitoring measures for the Sava and Danube Rivers. However, as a more relevant and superior outcome, it has been illustrated how different chemical analyses for preselected pollutants could lead to totally different ...
... ecosystems, which have become increasing serious problems for decades. Riverine contamin- ants are derived from both anthropogenic and biogenic sources.1–4 Anthropo- genic inorganic, organic and organometallic pollutants are emitted into rivers by for example runoffs and leaching from agricultural fields ...Milan Antonijević, Marija Arsović, Josef Cáslavský, Vesna Cvetković, Predrag Dabić, Mladen Franko, Gordana Ilić, Milena Ivanovic, Nevena Ivanović, Milica Kosovac, Dragana Medić, Slobodan Najdanović, Milica Nikolić, Jovana Novaković, Tatjana Radovanović, Djurdjina Ranić, Bojan Šajatović, Gorica Špijunović, Ivana Stankov, Jelena Tošović, Polonca Trebse, Olivera Vasiljević, Jan Schwarzbauer. "Actual contamination of the Danube and Sava rivers at Belgrade (2013)" in Journal of the Serbian Chemical Society, National Library of Serbia (2014). https://doi.org/10.2298/JSC131105014A
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Advantages and Disadvantages of a Parallel and Zigzag Method of Acquisition in Walking Mode in Magnetometric Archeological Research
магнетометријска испитивања, цик-цак и паралелна аквизиција у ходајућем моду, линеарне аномалије, археологија... Mining and Geology, Departman for geophysics, Serbia mirkopetkovic.90@gmail.com VESNA CVETKOV University of Belgrade, Faculty of Mining and Geology, Departman for geophysics, Serbia BRANISLAV SRETENOVIĆ University of Belgrade, Faculty of Mining and Geology, Departman for geophysics, Serbia 902.3:621 ...
... materials are the basic prerequisite for the application of geophysical methods to be successful. The use of iron-based materials during human history allows for the successful application of magnetometry, which is now one of the leading choices of geophysical methods for archaeologi- cal reconnaissance ...
... ey as for Fig 1. 97 Archaeology and Science 10 (2014)Petković et al - Advantages and Disadvantages of a Parallel...(93-110) Fig. 3a Contour map of a vertical gradient of TMI in N-S orientation. Key as for Fig 1. Fig. 3b Contour map of a vertical gradient of TMI in N-S orientation. Key as for Fig ...Mirko Petković, Vesna Cvetkov, Branislav Sretenović. "Advantages and Disadvantages of a Parallel and Zigzag Method of Acquisition in Walking Mode in Magnetometric Archeological Research" in Arheologija i prirodne nauke (2014)
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Parameter determination of soil oscillation law using quotient of the relative growth increments of oscillation velocity and reduced distances at “Nepričava“ open pit mine
... (8) By the replacement of values for K from (8) in the equation (5) we obtain the equation: 1 1 n R v v R (9) From the equation (9), for R = R1 there is obtained v = v1 for any n, in our case n > 0. For R = R1, i = 2, 3, ..., N, from the equation ...
... conditions of blasting and geologic characteristics of the soil, being determined on the basis of test blasting for the specific work environment. In this paper, an analysis of the method for the determination of soil oscillation law parameters has been conducted, suggested by Profesor M. A. Sadovski ...
... blasting, the determination of the soil oscillation velocity is enabled for each blast operation in advance, thus blasting is, as regards seismic effect, under control, which gives an opportunity to plan the magnitude of shock waves for each future blast operation (Trajković et al. 2005). In this manner ...Suzana Lutovac, Sanja Bajić, Marina Ravilić, Radmila Gaćina. "Parameter determination of soil oscillation law using quotient of the relative growth increments of oscillation velocity and reduced distances at “Nepričava“ open pit mine" in Underground Mining Engineering, Belgrade : University of Belgrade, Faculty of Mining and Geology (2015). https://doi.org/10.5937/podrad1526009L
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The influence of structural modification of Pd(II) pincer-type complexes on the kinetics of substitution reactions
Snežana Jovanović Stević, Snežana Radisavljević, Aleksandar Mijatović, Biljana Petrović, Ana Kesić (2023)This mini-review summarizes the kinetic data obtained for the substitution reactions of some palladium(II) complexes containing bis-pyrazolylpyridine derivatives as pincer-type ligands with biologically significant nitrogen- and sulfur-donor biomolecules as nucleophiles. Three structurally different palladium(II) complexes were selected: [Pd(L1)Cl]+ (Pd1), [Pd(L2)Cl]+ (Pd2) and [Pd(L3)Cl]+ (Pd3) (where L1 = bis(2-(1H-pyrazol-1-yl)ethyl)amine, L2 = 2,6-bis(5-(tert-butyl)-1H-pyrazol-3-yl)pyridine, and L3 = 2,6-bis(5-(tert-butyl)-1-methyl-1H-pyrazol-3-yl)pyridine, while for the entering nucleophiles were used thiourea (Tu), L-methionine (L-met), and guanosine-5’-monophosphate (5’-GMP). Kinetic measurements were carried out for all systems as pseudo-first ...Snežana Jovanović Stević, Snežana Radisavljević, Aleksandar Mijatović, Biljana Petrović, Ana Kesić. "The influence of structural modification of Pd(II) pincer-type complexes on the kinetics of substitution reactions" in 2nd International Conference on Chemo and BioInformatics ICCBIKG 2023, 28-29 September 2023, Institute for Information Technologies, University of Kragujevac, Serbia, Kragujevac : Institute for Information Technologies, University of Kragujevac (2023)
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Possibilities for Reduction of Energy-Related Air Pollution in Serbia - Exploring Energy Scenarios
Fossil fuels and biomass account for almost 93% of the total primary energy supply in Serbia. Meeting the energy needs of consumers implies a transformation of the chemical energy of fuels through combustion processes to obtain heat that can be utilized as such, or further transformed into mechanical or electrical energy. These processes have an undeniable impact on air pollution, even in cases of biofuels or hydrogen combustion. Possibilities for air pollution reduction are identified, both on the supply ...Marija Živković, Boban Pavlović, Dejan Ivezić, Aleksandar Mijatović. "Possibilities for Reduction of Energy-Related Air Pollution in Serbia - Exploring Energy Scenarios" in 9th International Conference Mining and Environmental Protection, 24.-27. May 2023, Sokobanja, Serbia, Belgrade, Serbia : University of Belgrade, Faculty of Mining and Geology (2023)
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Mesozoic carbonate rocks in Serbia used as dimension stone
Vesna Matović, Tijana Vojnović Ćalić (2016)The building industry in Serbia uses, to a great extent, imported natural stone for architectural purposes. The significance of local deposits, particularly limestones, is not adequately perceived despite the country’s abundance of these valuable resources. Therefore, this study focuses on Serbia’s Mesozoic carbonate rocks, specifically on the deposits of four selected quarries: Klisura, Skrzut, Struganik, and Tisnica. The quality and prospects of the application of these limestones has not yet been the subject of a detailed, comprehensive investigation. Therefore, ...... withdrawn SRPS B.B3.200 (1994) used for reference in this research. Therefore, the examined rocks are suitable for use as dimensional stone, as natural stone slabs for architectural cladding and paving for exterior and interior use. With the actual national standards for natural stone products, designers ...
... resistance) were examined for 52 collected samples. The laboratory tests were per- formed according to current national standards at tWO equally credible laboratories: the Laboratory of the High- way Institute (Laboratory for Stones and Stone Aggregates) and the Institute for Testing: of Materials-IMS ...
... their usability. For the appropriate use of natural stone products, it is advisable to consult suitable technical requirements. The alignment of Serbian national standards with the standards of the European Union is in progress. The requirements concerning natural stone slabs for cladding and ...Vesna Matović, Tijana Vojnović Ćalić. "Mesozoic carbonate rocks in Serbia used as dimension stone" in Bulletin of Engineering Geology and the Environment, Springer Science and Business Media LLC (2016). https://doi.org/10.1007/s10064-015-0722-0
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Развој модела конструкције просторија отварања рудника са подземном експлоатацијом
Dražana M. Tošić (2016-08-26)Приликом израде подземних просторија у стјенској маси долази до нарушавања природне равнотеже напонских стања стијенског масива који су владали прије израде тих просторија, при чему долази до појаве прертасподјеле напона и његове концентрације у појединим правцима и тачкама, односно долази до појаве пластичних деформација које су праћене ломљењем стијенске масе и кретањима материјала према откопаном простору...модел, метод коначних елемената, просторија отварања, напон, дефеормација стијенског масива, алгоритам функционалних зависностиDražana M. Tošić. "Развој модела конструкције просторија отварања рудника са подземном експлоатацијом" in Универзитет у Београду, Универзитет у Београду, Рударско-геолошки факултет (2016-08-26)
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2D geoelectrical resistivity tomography application at the former city waste dump "Ada Huja": Eco-geological problem
... stimulated fire. Monetary investments for this kind of a project can be steep, but it is of most importance to make a good economical calculation for taking a part in this kind of project. United States of America is a country that has the most initiative for methane exploitation with 519 plants ...
... communal waste dump in the year 1960. From then on it is representing an unsolved ecological problem. Such a solution for the daily production of waste causes several threats for the ecosystem such as the production of methane, hydrogen-sulfide, carbon-dioxide and carbon-monoxide. Based on the ...
... statistical reports on the health condition of the people who live in the near vicinity of the waste site indicates a neglecting attitude for the health of people, but also for the condition of the environment in general. This is best noticed in the completely wrong classification of forest classes in that ...Branislav Sretenović, Filip Arnaut, Ivana Vasiljević, Vesna Cvetkov. "2D geoelectrical resistivity tomography application at the former city waste dump "Ada Huja": Eco-geological problem" in Podzemni radovi, Centre for Evaluation in Education and Science (CEON/CEES) (2019). https://doi.org/10.5937/PodRad1934059S
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Insights into dike nucleation and eruption dynamics from high-resolution seismic imaging of magmatic system at the East Pacific Rise
Milena Marjanović, Suzanne M. Carbotte, Alexandre Stopin, Satish C. Singh, René-Édouard Plessix, Miloš Marjanović, Mladen R. Nedimović, Juan Pablo Canales, Hélène D. Carton, John C. Mutter, Javier Escartín (2023)Milena Marjanović, Suzanne M. Carbotte, Alexandre Stopin, Satish C. Singh, René-Édouard Plessix, Miloš Marjanović, Mladen R. Nedimović, Juan Pablo Canales, Hélène D. Carton, John C. Mutter, Javier Escartín. "Insights into dike nucleation and eruption dynamics from high-resolution seismic imaging of magmatic system at the East Pacific Rise" in Science Advances, American Association for the Advancement of Science (AAAS) (2023). https://doi.org/10.1126/sciadv.adi2698