Претрага
416 items
-
Numerical Models of Debris Flows with Entrainment Analysis-Case Studies from the Republic of Serbia
The results of material entrainment analysis in RAMMS debris flow software, as well as numerical models of final flow heights for two case studies from the Republic of Serbia are presented. Both of debris flow cases started with initial sliding of huge volume block, prolonging to behave as flowing process. Results of the analysis showed that entrainment material affects final results of transportation model, runout distance, deposition area and volume of debris flow. In both cases entrainment volume is very ...Jelka Krušić , Biljana Abolmasov, Miloš Marjanović. "Numerical Models of Debris Flows with Entrainment Analysis-Case Studies from the Republic of Serbia" in Understanding and Reducing Landslide Disaster Risk. WLF 2020. ICL Contribution to Landslide Disaster Risk Reduction, Springer, Cham (2021). https://doi.org/10.1007/978-3-030-60706-7_25
-
Advantages and Disadvantages of a Parallel and Zigzag Method of Acquisition in Walking Mode in Magnetometric Archeological Research
магнетометријска испитивања, цик-цак и паралелна аквизиција у ходајућем моду, линеарне аномалије, археологија... Contour m ap of a vertical gradient of TM I in E-W orientation. K ey as for Fig 1. Archaeology and Science 10 (2014) 100 Petković et al - Advantages and Disadvantages of a Parallel...(93-110) Fig. 5a Contour map of a vertical gradient of TMI in E-W orientation. Key as for Fig 1. 101 Archaeology ...
... Advantages and Disadvantages of a Parallel...(93-110) Fig. 5b Contour map of a vertical gradient of TMI in E-W orientation. Key as for Fig 1. Fig. 5c Contour map of a vertical gradient of TMI in E-W orientation. Key as for Fig 1. Archaeology and Science 10 (2014) 102 Petković et al - Advantages and ...
... Illustration of N-S orientation of traverses. Key: a. zigzag fashion; b. parallel fashion; c. mid-fi eld in parallel fashion. Fig. 2 Illustration of E-W orientation of traverses. Key as for Fig 1. 95 Archaeology and Science 10 (2014)Petković et al - Advantages and Disadvantages of a Parallel...(93-110) ...Mirko Petković, Vesna Cvetkov, Branislav Sretenović. "Advantages and Disadvantages of a Parallel and Zigzag Method of Acquisition in Walking Mode in Magnetometric Archeological Research" in Arheologija i prirodne nauke (2014)
-
Optimizacija parametara reza rotornog bagera pri otkopavanju materijala sa povećanom čvrstoćom
Saša D. Bošković (2016-09-09)Otkopavanje materijala rotornim bagerom je veoma sloţen fiziĉko-mehaniĉki proces. Pokazatelji efektivnosti tog procesa zavise od velikog broja raznovrsnih ĉinilaca od kojih se posebno mogu istaći: fiziĉko-mehaniĉke karakteristike materijala koji se otkopava, reţim rada bagera i izbor tehnoloških parametara bloka, odreska i reza, geometrije vedrica i zuba itd. Poseban problem se javlja kod otkopavanja materijala povećane ĉvrstoće, što je ĉest sluĉaj na našim površinskim kopovima. Dimenzionisanje specifiĉne sile kopanja bagera prema manjim masama izuzetno ĉvrstog materijala je neracionalno i rešenje ...rotorni bager, parametri reza, otpor na kopanje, dinamika bagera, kapacitet, optimizacija, specifična potrošnja energije... pretpostavki teorije tanke ploĉe imamo deformacije z=0, xz=0 i yz=0 i pomeranja w=w(x,y), u=-zy=-z w/x i v=-zx =-zw/y. Nepoznate deformacije glase: . yx w z2 x v y uγ , y w z y vε , x w z x uε 2 xy2 2 y2 2 x ...
... diferencijalnih operatora moţemo izvesti na osnovu definisanog vektora deformacije i pomeranja taĉke: . x w y w w yx 0 0 y 0 00 x zfL yx w z2 y w z x w z 2 2 2 2 2 2 ...
... tih relacija u jednaĉine momenta u preseku dobija se: , 6 )1( , )( , )( 232 2 2 2 2 2 2 2 2 yx wGt yx w DMM x w y w DM y w x w DM yxxy y x ...Saša D. Bošković. "Optimizacija parametara reza rotornog bagera pri otkopavanju materijala sa povećanom čvrstoćom" in Универзитет у Београду, Универзитет у Београду, Рударско-геолошки факултет (2016-09-09)
-
Effects of external noise on threshold-induced correlations in ferromagnetic systems
Dragutin Jovković, Sanja Janićević, Svetislav Mijatović, Lasse Laurson, Đorđe Spasojević. "Effects of external noise on threshold-induced correlations in ferromagnetic systems" in Physical Review E, American Physical Society (APS) (2021). https://doi.org/10.1103/PhysRevE.103.062114
-
Prognoza operativne efikasnosti aktivnog podzemnog rudnika zasnovana na teoriji sivih sistema
Svetlana M. Štrbac-Savić (2016-06-10)Efikasnost predstavlja preduslov za opstanak svake rudarske kompanije, posebno u uslovima izuzetno konkurentnog trţišnog okruţenja kao što je to rudarska industrija. Efikasnost oznaĉava sposobnost kompanije da ispuni svoje kratkoroĉne ili dugoroĉne ciljeve. Operativna efikasnost se definiše kao odnos izmeĊu ulaznih parametara potrebnih za odvijanje proizvodnje i pokazatelja dobijenih proizvodnjom. U kontekstu rudarskog poslovanja, operativna efikasnost se odnosi na vreme potrebno da se mineralno dobro transformiše u novĉana sredstva. Visoka operativna efikasnost se postiţe kada se ostvari prava kombinacija karakteristika ...podzemni rudnik, operativna efikasnost, prognoza, teorija sivih sistema, stohastiĉke diferencijalne jednaĉine, simulacija... 0 0 0 = . W t t W t W t t W t W t W t t W t W t t W t S t t S e S e S e e S t e Kako S(t+∆t) zavisi samo od budućeg priraštaja standardnog Braunovog kretanja W(t+∆t)-W(t) kako je standardno Braunovo kretanje proces Markova ...
... realan sluĉajni proces W(t), t≥0, tϵR, koji ima sledeće osobine: 1. W(0) = 0 skoro sigurno. 2. Proces W(t), t ≥ 0 ima nezavisne priraštaje tj. sluĉajne promenljive W(t1), W(t2)-W(t1), …, W(tm)-W(tm-1) su nezavisne, za 0=t0≤t1≤…≤tm. 3. Za 0 ≤ s < t priraštaj W(t) − W(s) ima N(0, t−s) raspodelu ...
... Braunovo kretanje Definicija 3.5.5: Neka je 0, 0, 0tW t W Vinerov sluĉajni proces, odnosno sluĉajni proces standardnog Braunovog kretanja. Stohastiĉki proces S(t) koji zadovoljava jednaĉinu 2 21 1 2 2 0 0, t tW W tS t S e S S e ...Svetlana M. Štrbac-Savić. "Prognoza operativne efikasnosti aktivnog podzemnog rudnika zasnovana na teoriji sivih sistema" in Универзитет у Београду, Универзитет у Београду, Рударско-геолошки факултет (2016-06-10)
-
Crystallography and Surface Oxidation of Stoichiometric Arsenopyrite from Šumadija-Kopaonik Pb-Zn/Polymetallic Ore District (Serbia)
Ivana Jelić, Aleksandar Pačevski, Aleksandar Kremenović, Aleš Šoster, Andreja Šestan, Janez Zavašnik (2023)The behaviour and stability of arsenopyrite largely depend on its crystal structure, but studies of crystallography and structural defects are scarce. For clarification, we investigated a series of natural arsenopyrite crystals from the polymetallic Pb-Zn-(±Cu,Ag,Au,Sb,Bi,W) Šumadija-Kopaonik ore district (Serbia) by powder X-ray diffraction (XRPD). Among them, samples from the Drenjak gold mineralisation showed near-stoichiometric FeAsS composition and were further investigated by conventional and high-resolution transmission electron microscopy methods. TEM revealed abundant planar crystallographic defects and epitaxial surface oxide layer ...Inorganic Chemistry, Condensed Matter Physics,General Materials Science, General Chemical Engineering, crystal structure, FeAsS, oxidation, TEM, XRPD... 2—Rujak (Apy-Py veins), 3—Drenjak (Au mineralisation in Apy vein), 4—Sastavci (Pb-Zn mine), 5—Trepča (Pb-Zn mine), 6—Golijska reka (W-Mo-Bi mineralisation), 7—Jurija (W mineralisation). (c,d) SEM-BSE micrographs of characteristic arsenopyrite samples from (c) Drenjak and (d) Sastavci locations, the ...
... structural defects are scarce. For clarification, we investigated a series of natural arsenopyrite crystals from the polymetallic Pb-Zn-{+Cu,Ag,Au,Sb,Bi,W) Šumadija- Kopaonik ore district (Serbia) by powder X-ray diffraction (XRPD). Among, them, samples from the Drenjak gold mineralisation showed ne ...
... these shortcomings, through X-ray powder diffraction (XRPD), we analysed a set of 14 arsenopyrite samples from polymetallic Pb-Zn-{+Cu,Ag,„Au,Sb,Bi,W) miner- alisations from the Šumadija–Kopaonik ore district, Serbia (Figure 1a,b), with different post-magmatic processes of deposition, mineral a ...Ivana Jelić, Aleksandar Pačevski, Aleksandar Kremenović, Aleš Šoster, Andreja Šestan, Janez Zavašnik. "Crystallography and Surface Oxidation of Stoichiometric Arsenopyrite from Šumadija-Kopaonik Pb-Zn/Polymetallic Ore District (Serbia)" in Crystals, MDPI AG (2023). https://doi.org/10.3390/cryst13020278
-
Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... l. Pharmaceutics 2021, 13, 1188 4 of 19 Table 1. Composition of developed nanocrystal dispersions. Formulation DK-I-60-3 (% w/w) SLS (% w/w) PVP (% w/w) Water (% w/w) SLS:PVP Ratio F1 0.20 0.02 0.20 to 100 1:10 F2 0.20 0.02 0.08 to 100 1:4 F3 0.20 0.02 0.04 to 100 1:2 F4 0.20 0.02 0.02 to 100 1:1 ...
... nanocrystal dispersions preparation, a modified wet ball milling technique was applied, similarly to the procedure explained earlier [13]. DK-I-60-3 (0.2% w/w) was homog- enized in aqueous stabilizer solution for 5 min at 10,000 rpm on a rotor stator homogenizer IKA Ultra-Turrax® T25 digital (IKA®-Werke GmbH ...
... in the commercial pharmaceutical development process. Int. J. Pharm. 2013, 453, 142–156. [CrossRef] [PubMed] 5. Alhalaweh, A.; Alzghoul, A.; Kaialy, W.; Mahlin, D.; Bergström, C.A. Computational predictions of glass-forming ability and crystallization tendency of drug molecules. Mol. Pharm. 2014, 11 ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
-
From post-disaster landslides inventory to open landslides data
Biljana Abolmasov, Miloš Marjanović, Uroš Đurić, Jelka Krušić. "From post-disaster landslides inventory to open landslides data" in Proceedings of 3rd European Regional Conference of IAEG/ Athens/ Greece/ 6-10 October 2021, International Association for Engineering Geology and the Environment (2021)
-
Synergy between the mineral deposit exploration and geothermal resources assessment on the example of "Valjevo" boron and lithium deposit in Serbia
Nebojša Atanacković, Vladimir Živanović, Ana Vranješ, Sava Magazinović, Marinko Toljić, Ana Arifović, Branislav Potić (2023)Exploration of mineral deposits involves a collection of vast data sets on geological characteristics of the area. These data can largely contribute to the assessment of the geothermal potential, which can lead to an increase in the share of geothermal resources in the energy mix of the extractive industry and the local community. On the example of the "Valjevo" B-Li deposit, data on structural settings and previous hydrogeological investigations were combined with the results of resource drilling and geophysical ...... Valjevo i L-34-137 Gornji Milanovac [6, 7} The basins spread in E-W direction with a maximal thickness around 900 m in central parts. The tectonic framework comprises older NE-SW and NW-SE faults, later overprinted with major E-W normal faults. Although the tectonic setting: of the basin is complex ...
... structural pattern, including the basin margins, where Mesozoic and Paleozoic sediments outcrop on the surface. 7,410,000 7,412,000 7,414,000 „420, a w 7,424,000 7,426,000 7,428,000 7,430,000 » A NZ ELB drillhole 4, 91 0, 00 0 Water temperature *C 11 - 20 e 21-30 e 31-40 4, 90 8, 00 0 ...
... gradient isoline Geothermal gradient map *Cilm 0.031 - 0.040 0.041 - 0.050 0.051 - 0.060 0.061 - 0.070 || 0.071 - 0.080 4, 90 4, 00 0 w E ganja Beloševa s Z> —— 0 0.5 1 1.5 2 cG -- III= _ wwiw= _ -km| / | ___ 0.081 - 0.090 0.091 - 0.100 N ——— ,9 02 ,0 00 4, Figure 4 ...Nebojša Atanacković, Vladimir Živanović, Ana Vranješ, Sava Magazinović, Marinko Toljić, Ana Arifović, Branislav Potić. "Synergy between the mineral deposit exploration and geothermal resources assessment on the example of "Valjevo" boron and lithium deposit in Serbia" in Proceedings 9th International Conference mining and environmental protection, MEP23, Sokobanja, 24-27th May 2023, Beograd : Univerzitet u Beogradu, Rudarsko-geološki fakultet (2023)
-
Верификација етажних транспортера на угљеном систему – површински коп Дрмно
Тамара Андрејевић (2024)У савременом рударству, површински копови угља наилазе на различите проблеме које треба превазићи зарад добијања потребне количине угља. Као највећи потрошачи овог енергента јављају се термоелектране, где на основу овога можемо да закључимо колико су блиско повезани добра и континуирана производња на површинском копу и рад термоелектрана. Са циљем да се обезбеди стабилна и континуирана производња, потребно је да се направи добар одабир транспортера. У овом раду, за потребе верификације затезне чврстоће траке и снаге погона транспортера, коришћен је ...... Caki lmg ep uh [0%0_]| cewA || co |omemAese - OM Mep | ___ y sea |Eloneees =s sabezo Bl hezbek 3 —a e __I el = JOA W |{1100 les |325 | ConveyorMo d LI a ! ı |-- -MNI OA a - [| w |r FI MNA F = LOLO === • [ % • t J H >= -EO = q KO b + N BenLoad CapcfyUbed eg NM E R i i N N N EI ...
... YcpojeHu TMn Tpake UlpviHa Tpake 1800 YkynHa ne0rbuHa Tpake 29.40 YkynHa penykoBaHa Maca Tpake 82 Maca TpaHcnoproBaHor MaTepvjana - W„ 190.7 YkynHa waca Tpake (W; x JI) 266443 Tlonauu o noroHy Bpoj noroHckvX 6y6Rb5eBa (O6yxBaTHM yrao (ykynHM) 'bakTop noroHa np\ kpeTaHoy KoedwujeHT Tpebba ...
... YcpojeHu TMn Tpake UlpviHa Tpake 1800 YkynHa ne0rbuHa Tpake 29.40 YkynHa penykoBaHa Maca Tpake 82 Maca TpaHcnoproBaHor MaTepujana - W„ 190.7 YkynHa waca Tpake (W., x JI) 263171 Tlonauu o noroHy Bpoj noroHckvX 6y6wbbeBa (O6yxBaTHM yrao (ykynHM) 'bakTop noroHa np\ kpeTaHoy KoedwujeHT Tpebba ...Тамара Андрејевић. Верификација етажних транспортера на угљеном систему – површински коп Дрмно, 2024
-
Метода променљивих околина за решавање проблема p-центра са поузданом мрежом
У овом раду је разматран проблем p-центра са поузданом мрежом (енгл. Reliable p-center facility location problem - RpCFLP). Решавање проблема подразумева иницијално успостављање p ресурса и алокације корисника, као и накнадну реалокацију корисника у складу са новонасталим сценаријима који садрже информације о онеспособљеним ресурсима и осталим измењеним улазним подацима. За решавање посматраног проблема предложена је метахеуристика заснована на итеративној варијанти основне методе променљивих околина (енгл. Iterated basic variable neighborhood search - IBVNS). Резултати тестирања предложене метахеуристике указују на њену ...Јована Рађеновић, Стефан Мишковић, Оливера Станчић. "Метода променљивих околина за решавање проблема p-центра са поузданом мрежом" in 50. Међународни симпозијум о операционим истраживањима SYM-OP-IS, Тара, Србија, 18-21.9.2023, Београд : Медија центар „Одбрана” (2023)
-
Aлтерације перидотита контролисане карактером флуида на примеру харцбургита Рудника - Серпентинизација или талкизација?
Стефан Петровић, Наталија Батоћанин (2020)У раду су приказани резултати испитивања серпентинисаних харцбургита Брђана (43°58'45.1" СГШ, 20°25'12.6" ИГД) и талкизираних харцбургита откривених у интервалу 429-559.8 m у истражној бушотини 330А/18 (44°07'33.2" СГШ, 20°30'28.5" ИГД) на Руднику. Узорци оба локалитета показују карактеристике резидуалних харцбургита из омотача, односно тектонита; лепидобластичне, бластозрнасте, или порфирокластичне структуре и масивне текстуре. Серпентинисани харцбургити и серпентинити Брђана су изграђени од серпентина, ретких реликата оливина и ортопироксена, акцесорног спинела, и веома ретког секундарног магнезита и магнетита. Најдоминантнији састојак (местимично гради и преко ...... list Čačak. Zavod za geološka i geofizička ispitivanja, Beograd DEER, W. A., HOWIE, R. A., ZUSSMAN, J. (1971): Rock-Forming Minerals, vol. 3. Longman William Clowes & Sons Ltd., London, Beccles and Colchester, 270 pp. DEER, W. A., HOWIE, R. A., ZUSSMAN, J. (1972): Rock-Forming Minerals, vol. 5. Longman ...
... (2010-14): Strukturno-geološka istraživanja sa izradom karte 1:2000 ležišta Rudnik. Fond stručnih dokumanata rudnika „Rudnik”, Rudnik. EVANS, W. B., JOHANNES, W., OTTERDOOM, H., TROMMSDORFF, V. (1976): Stability of chrysotile and antigorite in the serpentine multisystem. Schweiz. Mineral. Petrogr. Mitt ...
... O. (1978): Osnovna geološka karta SFRJ 1:100000. Tumač za list Gornji Milanovac L34-137. Savezni geološki zavod, Beograd. MARTIN, B., FYFE, S. W. (1970): Some experimental and theoretical observations on the kinetics of hydration reactions with particular reference to serpentinization. Chem. Geol ...Стефан Петровић, Наталија Батоћанин. "Aлтерације перидотита контролисане карактером флуида на примеру харцбургита Рудника - Серпентинизација или талкизација?" in Записници српског геолошког друштва, Српско геолошко друштво, Београд (2020)
-
Extensive vibrations of the belt conveyer drive electromotor of a bucket wheel excavator as a result of intesified wear-and-tear of its mount support
Vesna Damnjanović, Predrag Jovančić, Snežana Aleksandrović. "Extensive vibrations of the belt conveyer drive electromotor of a bucket wheel excavator as a result of intesified wear-and-tear of its mount support" in Journal of Vibroengineering (2017). https://doi.org/10.21595/jve.2016.17321
-
Laboratory Testing of Nanosilica- Reinforced Silicate and Polyacrylamide Gels
Irina Zahirovic, Dušan Danilović, Milica Šuput Vranjin, Miloš Tripković. "Laboratory Testing of Nanosilica- Reinforced Silicate and Polyacrylamide Gels" in SPE Journal (2023)
-
The Potential of Biomarkers to Distinguish Lower and Middle Miocene Lignites from the Coal-Mining District of Lusatia
... samples. References Bechtel, A., Sachsenhofer, R.F., Markic, M., Gratzer, R., Lücke, A., Püttmann, W., 2003. Organic Geochemistry 34, 1277–1298. Kus, J., Dolezych, M., Schneider, W., Hofmann, T., Visiné Rajczi, E., 2020. International Journal of Coal Geology 217, 103283. Nytoft, H.P. ...I. Kojic, J. Kus, D. Zivotic, K. Stojanovic. "The Potential of Biomarkers to Distinguish Lower and Middle Miocene Lignites from the Coal-Mining District of Lusatia" in 30th International Meeting on Organic Geochemistry (IMOG 2021), European Association of Geoscientists & Engineers (2021). https://doi.org/10.3997/2214-4609.202134092
-
Introduction to special section: Characterization of hydrocarbon and geothermal resource potential and carbon sequestration opportunities of the Pannonian Basin
Balázs Németh, Gábor Tari, Gábor Bada, Dejan Radivojević, Bruno Tomljenovic, Csaba Krézsek. "Introduction to special section: Characterization of hydrocarbon and geothermal resource potential and carbon sequestration opportunities of the Pannonian Basin" in Interpretation, AAPG SEG (2018). https://doi.org/10.1190/INT-2017-1207-SPSEINTRO.1
-
Одређивање оптималне производње дубинске пумпе на клипним шипкама
Небојша Савић (2024)Дужи временски период током историје производње нафте, дубинске пумпе на клипним шипкама су први и у многим случајевима једини избор када су у питању механичке методе експлоатације. Правилан одабир сваког појединачног елемента система омогућава оптимизацију која са собом повлачи бенефите у виду повећавања ефикасности и смањења трошкова. Тренутно примењени систем дубинских пумпи на клипним шипкама на лежишту „Н“ обезбеђује стабилну производњу и реализацију годишњих планова производње без већих проблема. У овом раду је приказан начин оптимизације производње дубинским пумпама ...... Downirake = FI H k i J 40000 š Pl EOM ELUJ 300 z i /_\ -20000 . eevdikai 200 M z i a 30000 10000 10000 / \ Šl GretorRareg ”| - a LUNI: I W W E BE E E - D M BD 90 120 150 180 210 240 270 300 990 380 PoškikiiBii Cidnk Al (diiyečs} Cnuka 5.5. Ipaduuku npukas pe3xynmama sa 6yuiomuny H-061 ...
... TIpolieca HIyMHaF4a. 3a HOBE BCHTHJIĆ pe3JiHuHTHX IHIpeuHMHMKa OTKJOH OOJMKa KyIJMHIC OJ uJleajtHe cib)epHuHocTu He cMe Ouru Behu oJ 1 no 4 um. = . W G — — — Cnuka 3.3.Koncmpykuuja ycucHoz eeHmu.na ( Jenuhi M,. Uuketu M., 2006. Texnonozuja npou3eoonbe nadi,me 0yOuncku upnkaMa, Ceeyuunuuume ...
... 3a yceaatbe: C-"Cup" r M - exaguug:H THH Mecro yceaamba mysme: A - spx B-amo T – aHo nokpeTEHH IIAp Tn nuH:iHH;ipa 3a wera.mHii K-Tim: W - ragax: a H - ojasasn 3 L - najnep 3a K-amum ca MeKIHM HaK0BalbeM: S - ragag 31 P - ojasas 38 Tim myyme: R - nHcepr T - ryGnHr TipeunHk ...Небојша Савић. Одређивање оптималне производње дубинске пумпе на клипним шипкама, 2024
-
Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... characterization. Drug Dev. Ind. Pharm. 44 (9), 1458–1466. https://doi.org/10.1080/03639045.2018.1460377. Holzer, M., Vogel, V., Mšntele, W., Schwartz, D., Haase, W., Langer, K., 2009. Physico- chemical characterisation of PLGA nanoparticles after freeze-drying and storage. Eur. J. Pharm. Biopharm. ...
... 'Trenkenschuh, E., Friess, W., 2021. Freeze-drying of nanoparticles: how to overcome colloidal instability by formulation and process optimization. Eur. J. Pharm. Biopharm. 165, 345–360. https://doi.org/10.1016/j.ejpb.2021.05.024. 'Trenkenschuh, E., Savšek, U., Friess, W., 2021. Formulation, process ...
... 3+2 100 90 Tr an sm it ta nc e (% ) u T T T ı T T—— 3500 3400 3300 3200 3100 3000 2900 Wavenumber (cm") ~ e o o O |- o O w – o O o o o ı lı 1. Tr an sm it ta nc e (% ) -= o i - I — — ——— 980 960 940 920 Wavenumber (cm ) 1000 Fig. 7. FT-IR spectra ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
-
Formative evaluation of e-learning projects with the logical framework approach
... Management. Un approccio sistemico alla gestione dei progetti, Isedi, Torino, 2007. [10] W. K. Kellogg Foundation, Logic Model Development Guide, available at: www.wkkf.org (accessed january 2014), 2004. [11] W. K. Kellogg Foundation, Evaluation Handbook, available at: www.wkkf.org (accessed november ...
... interventi formativi, Carocci, Roma, 2004. [3] Bezzi C., Il disegno della ricerca valutativa, Angeli, Milano, 2001. [4] Rossi P. H., Lipsey M. W., Freeman H. E., Evaluation: A Systematic Approach, SAGE publications, Thousand Oaks, CA, 2003. [5] Palumbo M., Il processo di valutazione. Decidere ...
... Commerce, Managing Successful Programmes: Delivering Business Change in Multi-Project Environments, HM Stationary Office, London, 2005. [14] Shadish W. R., Cook T. D., Leviton L. C., Foundations of program evaluation: Theories of practice, Sage, Newbury Park, CA, 1991. [15] Sangrà A., Vlachopoulos ...Roberto Linzalone, Giovani Schiuma, Ivan Obradović, Ranka Stanković. "Formative evaluation of e-learning projects with the logical framework approach" in The Sixth International Conference on e-Learning (eLearning-2015), September 2015, Belgrade, Serbia, Belgrade Metropolitan Univesity (2015)
-
Underground loading-haulage equipment selection with application of topsis method with different weighting methods of criteria
The choice of adequate mining machines is one of the most complex problems in the underground exploitation of mineral raw materials. The weight of such a decision is reflected in the high prices of these machines and the occurrence of even greater costs during their use if their choice was wrongly conceived. There are numerous examples from practice in which such decisions were made solely on the basis of comparing the prices of machines, without considering any of the ...utovarno-transportna mehanizacija, izbor, TOPSIS, entropija, standardna devijacija, težina kriterijumaVladimir Krivošić, Luka Crnogorac, Rade Tokalić. "Underground loading-haulage equipment selection with application of topsis method with different weighting methods of criteria" in Underground mining engineering, University of Belgrade - Faculty of Mining and Geology (2024)