Претрага
637 items
-
Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... solubility in water and oils, melting tempera- ture, crystallinity, and amorphization ability, formulation steps can be determined using a knowledge-based approach. Generally, poorly soluble substances can be characterized as brick dust or grease balls depending on the limiting factor for the solubility: solid-state ...
... reduced food effects [7,10]. Because absorption of poorly soluble drugs can be altered in different prandial states, designing a formulation resistant to food effects early in drug development is beneficial. Additionally, it can provide a commercial advantage and prevent costly reformulation later in ...
... showed that sample S5 (suspension that corresponds to formulation F5) predominantly contained crystalline DK-I-60-3 but not SLS, as can be seen from Figure 5a. This can be explained by SLS being in an amorphous state or lost during sample preparation due to incomplete attachment on the particle surface ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
-
Stratigraphy and Microfauna (Radiolarians and Foraminifera) of the Upper Cretaceous (Upper Santonian–Lower Campanian) Carbonate Deposits in the Area of Struganik Village, Western Serbia)
Santonian, Campanian, radiolarians, planktonic foraminifera, biostratigraphy, limestones, Struganik, SerbiaLiubov Bragina, Nikita Bragin, Luidmila Kopaevich, Nevenka Đerić, Nataša Gerzina Spajić. "Stratigraphy and Microfauna (Radiolarians and Foraminifera) of the Upper Cretaceous (Upper Santonian–Lower Campanian) Carbonate Deposits in the Area of Struganik Village, Western Serbia)" in Stratigraphy and Geological Correlation, Pleiades Publishing Ltd (2020). https://doi.org/10.1134/S0869593820010037
-
A Model for Determining the Dependability of Continuous Subsystems in Coal Mines Using the Fuzzy Logic Approach
Nikola Stanić, Miljan Gomilanović, Petar Marković, Daniel Krzanović, Aleksandar Doderović, Saša Stepanović (2024)This study presents a unique model for assessing the dependability of continuous parts of combined systems in open-pit mining through the application of fuzzy logic. Continuous sub-systems as part of the combined system of coal exploitation in surface mines have the basic function of ensuring safe operation, high capacity with high reliability, and low costs. These subsystems are usually part of the thermal power plant’s coal supply system and ensure stable fuel supply. The model integrates various independent partial ...fuzzy logic, max-min composition, continuous part of combined system (CCS), open pit, mining, dependabilityNikola Stanić, Miljan Gomilanović, Petar Marković, Daniel Krzanović, Aleksandar Doderović, Saša Stepanović. "A Model for Determining the Dependability of Continuous Subsystems in Coal Mines Using the Fuzzy Logic Approach" in Applied Sciences, Basel, August 2024, MDPI (2024). https://doi.org/https://doi.org/10.3390/app14177947
-
A Data Driven Approach for Raw Material Terminology
Olivera Kitanović, Ranka Stanković, Aleksandra Tomašević, Mihailo Škorić, Ivan Babić, Ljiljana Kolonja (2021)The research presented in this paper aims at creating a bilingual (sr-en), easily searchable, hypertext, born-digital, corpus-based terminological database of raw material terminology for dictionary production. The approach is based on linking dictionaries related to the raw material domain, both digitally born and printed, into a lexicon structure, aligning terminology from different dictionaries as much as possible. This paper presents the main features of this approach, data used for compilation of the terminological database, the procedure by which it has ...sirovine, rudarstvo, terminologija, rečnik, terminološka aplikacija, mobilna aplikacija, digitizacija, leksički podaci, korpusi, otvoreni povezani podaci... y no limitations to the amount of data that can be added, including multimedial data, which results in better quality data. Various search options and different possibilities of database organization contribute to the efficiency of access. Dictionaries can be easily customized for specific needs of users’ ...
... senses per each term, described by a definition, and labeled by small letters a, b, c,. . . , u. Each individual sense can be related to one or more other terms in the dictionary, and it can be followed by its bibliographic source. Digitization of DMMRT yielded 28,757 terms with a total of 37188 sense definitions ...
... with reference to the original source. All of the structures can, in general, be mapped to the union of the structures of the two dictionaries presented in more detail, MD and DMMRT. Thus, a terminological entry in the common database can consist of a headword (list), rarely part- of-speech, equivalent(s) ...Olivera Kitanović, Ranka Stanković, Aleksandra Tomašević, Mihailo Škorić, Ivan Babić, Ljiljana Kolonja. "A Data Driven Approach for Raw Material Terminology" in Applied Sciences, MDPI AG (2021). https://doi.org/10.3390/app11072892
-
Српски језик у дигиталном добу -- The Serbian Language in the Digital Age
Duško Vitas, Ljubomir Popović, Cvetana Krstev, Ivan Obradović, Gordana Pavlović-Lažetić, Mladen Stanojević (2012)... language – and again his technology simply made analogue copies. Language technology can now simplify and automate the processes of translation, content production, and knowledge management for all European languages. It can also empower intuitive speech-based interfaces for household electronics, machinery ...
... soware are just some of the application areas in which language technology can play an important role. e popularity of social media applications like Twitter and Facebook suggest a need for sophisticated language technologies that can monitor posts, summarise discussions, suggest opinion 45 trends, detect ...
... locative (see Fig- ure 3). ere are five oblique cases in Serbian, which can all be combined with prepositions (the locative al- ways is). All these cases and prepositional phrases are polysemous. Conversely, the same meaning can occa- sionally be expressed by different cases or prepositional phrases ...Duško Vitas, Ljubomir Popović, Cvetana Krstev, Ivan Obradović, Gordana Pavlović-Lažetić, Mladen Stanojević. "Српски језик у дигиталном добу -- The Serbian Language in the Digital Age" in META-NET White Paper Series, G. Rehm, H. Uszkoreit (eds.), Springer (2012)
-
Testing the energy value of different types of coal by the method of active thermography
In this paper, coal thermograms are presented and analyzed in order to determine their energy value. Two types of coal of different categories, brown and lignite, were selected for active thermographic imaging. The tested coal samples were processed before measurement so that they are similar in dimensions and have two plane-parallel smooth surfaces. The test samples were "primarily" heated under the same conditions and the process of their cooling was monitored by a thermal camera. "Then" they were cooled ...Stevan Đenadić, Ljubiša Tomić, Vesna Damnjanović, Predrag Jovančić, Dragutin Jovković. "Testing the energy value of different types of coal by the method of active thermography" in 9th International Scientific Conference on Defensive Technologies, Belgrade, Serbia, 15-16 October 2020, The Military Technical Institute (2020)
-
Application of Thermal Imaging in Surface Mining
Milanka Negovanović (2022)Termalno snimanje se sve više koristi u rudarskoj industriji kao jedan od dijagnostičkih alata za praćenje određenih proizvodnih procesa, kao i stanja opreme i mašina. Predstavlja nedestruktivnu i beskontaktnu metodu ispitivanja koja omogućava rano otkrivanje problema, planiranje održavanja sa minimalnim kvarovima, sprečavanje neplaniranih poremećaja, posmatranje materijala u nepristupačnim ili opasnim područjima i poboljšanje bezbednosti i produktivnosti. Termalno snimanje koristi specijalizovane termalne kamere sa unutrašnjim detektorima koji identifikuju veoma male temperaturne varijacije i proizvode sliku tog nevidljivog infracrvenog ili toplotnog ...Termalno snimanje, nedestruktivne metode testiranja, površinska eksploatacija, termalne kamere, rudarske operacijeMilanka Negovanović. "Application of Thermal Imaging in Surface Mining" in 15th International Conference OMC 2022, Zlatibor, 12-15th October 2022, Jugoslovenski komitet za površinsku eksploataciju (2022)
-
Nonequilibrium athermal random-field Ising model on hexagonal lattices
Svetislav Mijatović, Dragutin Jovković, Đorđe Spasojević. "Nonequilibrium athermal random-field Ising model on hexagonal lattices" in Physical Review E, American Physical Society (APS) (2021). https://doi.org/10.1103/PhysRevE.103.032147
-
Strategic Environmental Assessment in the Application of Preventive Protection for Wind Farm Noise—Case Study: Maestrale Ring Wind Farm
Determining the spatial position of wind turbines is the initial and most important phase in the development of a wind farm project. In this sensitive phase, all potential problems that may arise in the later stages of project development should be prevented by means of spatial and urban planning instruments. This makes it possible to achieve maximum use of the potential of wind in a particular space and, thus, fulfil the technical and economic requirements of the project while ...Energija,energetski inženjering i elektroenergetska tehnologija,obnovljivi izvori energije, održivost i životna sredina,električni i elektronski inženjering,kontrola i optimizacija,inženjering... turbines—Fact, fiction or deception. Can. Acoust. 2006, 34, 29–36. 68. Bell, J.A. Annoyance from wind turbines: Role of the middle ear muscles. Acoust. Aust. 2014, 42, 57. 69. Jeffery, R.D.; Krogh, C.M.E.; Horner, B. Industrial wind turbines and adverse health effects. Can. J. Rural Med. 2014, 19, 21–26 ...
... solutions for the possible key spatial impacts of wind power with regard to noise, shadow flicker, ornithofauna and chiropterofauna. The weakness of SEA can be seen in its predominant application of expert qualitative methods that bring with them subjec- tivity, since they depend on expert knowledge and ...
... each of the mentioned territorial impacts is especially important for determining the optimal number and position of wind turbines. This analysis can be partial (the authors use the term “partial” for all assessments that analyze the impact of a particular project, e.g., wind farms, on only one ...Boško D. Josimović, Aleksandar Cvjetić, Božidar Manić. "Strategic Environmental Assessment in the Application of Preventive Protection for Wind Farm Noise—Case Study: Maestrale Ring Wind Farm" in Energies, MDPI AG (2021). https://doi.org/10.3390/en14196174
-
Assessing Criteria Weights by the Symmetry Point of Criterion (Novel SPC Method) - Application in the Efficiency Evaluation of the Mineral Deposit Multi-Criteria Partitioning Algorithm
Information about the relative importance of each criterion or the weights of criteria can have a significant influence on the ultimate rank of alternatives. Accordingly, assessing the weights of criteria is a very important task in solving multi-criteria decision-making problems. Three methods are commonly used for assessing the weights of criteria: objective, subjective, and integrated methods. In this study, an objective approach is proposed to assess the weights of criteria, called SPC method (Symmetry Point of Criterion). This point ...Вишекритеријумско одлучивање, тежине критеријума, тачка симетрије критеријума, налазиште минерала, алгоритам, процена учинкаZoran Gligorić, Miloš Gligorić, Igor Miljanović, Suzana Lutovac, Aleksandar Milutinović. "Assessing Criteria Weights by the Symmetry Point of Criterion (Novel SPC Method) - Application in the Efficiency Evaluation of the Mineral Deposit Multi-Criteria Partitioning Algorithm" in Computer Modeling in Engineering & Sciences (2023). https://doi.org/10.32604/cmes.2023.025021
-
Agent-based modeling as a support to an expert-based approach: Exploring individual heating systems transition
Expert-based energy scenarios are mainly developed following assumptions of experts and, in most cases, a limited number of stakeholders. Such an approach will provide satisfactory results in centrally managed energy sectors where further decisions could be envisaged relatively precisely (electricity production/distribution, district heating systems, etc.). The same approach will provide more uncertain outcomes of future energy structure in the household sector, where decisions related to consumption, selection of energy source, or application of specific technology are made by numerous ...Energetska tranzicija, Grejanje domaćinstava, Individualni sistemi grejanja, Energetsko planiranje, Integrisano energetsko planiranje, ABM, LEAP, SrbijaBoban Pavlović, Marija Živković, Dejan Ivezić. "Agent-based modeling as a support to an expert-based approach: Exploring individual heating systems transition" in South East European Conference on Sustainable Development of Energy, Water and Environment Systems 22 – 26 May 2022, Vlorë, Albania, Faculty of Mechanical Engineering and Naval Architecture, Zagreb (2022)
-
Characterization and Environmental Evaluation of Recycled Aggregates from Construction and Demolition Waste in Belgrade City Area (Serbia)
Filip Abramović, Miroslav Popović, Vladimir Simić, Vesna Matović, Radmila Šerović. "Characterization and Environmental Evaluation of Recycled Aggregates from Construction and Demolition Waste in Belgrade City Area (Serbia)" in Materials, MDPI AG (2024). https://doi.org/10.3390/ma17040820
-
Terminology Acquisition and Description Using Lexical Resources and Local Grammars
Acquisition of new terminology from specific domains and its adequate description within terminological dictionaries is a complex task, especially for languages that are morphologically complex such as Serbian. In this paper we present an approach to solving this task semi-automatically on basis of lexical resources and local grammars developed for Serbian. Special attention is given to automatic inflectional class prediction for simple adjectives and nouns and the use of syntactic graphs for extraction of Multi-Word Unit (MWU) candidates for ...... lemmas. Figure 1: Diagram of terminology acquisition using lexical resources and local grammars The newly acquired terms, both simple and MWU, can be exported to termbases, TBX and other standard formats for terminological re- sources. In this paper we will focus on (marked Proceedings of the ...
... of lemmas (DELAS) each lem- ma is described in full detail so that a dictionary of forms containing all necessary grammatical information (DELAF) can be generated from it, and subsequently used in various NLP tasks. Serbian e-dictionaries of simple forms have reached a considerable size: they ...
... for verbs account for 59.6% of lemmas. Figure 3: FST classes and the percentage cover- ing the dictionary of lemmas FST class prediction can be divided into two parts: one is extraction of implicit knowledge and the other is actual prediction of FST class for a new lemma. Extraction of ...Cvetana Krstev, Ranka Stanković, Ivan Obradović, Biljana Lazić. "Terminology Acquisition and Description Using Lexical Resources and Local Grammars" in Proceedings of the 11th Conference on Terminology and Artificial Intelligence, Granada, Spain, 2015, Granada : LexiCon (Universidad de Granada) (2015)
-
Mechanosynthesis and structural characterization of nanocrystalline Ce1–Y O2– (x=0.1–0.35) solid solutions
Martin Fabián, Bratislav Antić, Vladimír Girman, Milica Vučinić-Vasić, Aleksandar Kremenović, Shigeru Suzuki, Horst Hahn, Vladimír Šepelák (2015)A series of nanostructuredfluorite-type Ce1–xYxO2–δ (0rxr0.35) solid solutions, prepared via highenergy milling of the CeO2/Y2O3mixtures, are investigated by XRD, HR-TEM, EDS and Raman spectroscopy. For thefirst time, complementary information on both the long-range and short-range structural features of mechanosynthesized Ce1–xYxO2–δ, obtained by Rietveld analysis of XRD data and Raman spectroscopy, is provided. The lattice parameters of the as-prepared solid solutions decrease with increasing yttrium content. Rietveld refinements of the XRD data reveal increase in microstrains in the host ceria ...Martin Fabián, Bratislav Antić, Vladimír Girman, Milica Vučinić-Vasić, Aleksandar Kremenović, Shigeru Suzuki, Horst Hahn, Vladimír Šepelák. "Mechanosynthesis and structural characterization of nanocrystalline Ce1–Y O2– (x=0.1–0.35) solid solutions" in Journal of Solid State Chemistry, Elsevier BV (2015). https://doi.org/10.1016/j.jssc.2015.06.027
-
Geochemical evaluation of dolostone deposits in Montenegro: Implications for potential industrial applications
Darko Bozovic, Vladimir Simic, Dragan Radulovic, Slobodan Radusinovic, Vesna Matovic, Anja Terzic (2024)This study presents a unique model for assessing the dependability of continuous parts of combined systems in open-pit mining through the application of fuzzy logic. Continuous sub-systems as part of the combined system of coal exploitation in surface mines have the basic function of ensuring safe operation, high capacity with high reliability, and low costs. These subsystems are usually part of the thermal power plant’s coal supply system and ensure stable fuel supply. The model integrates various independent partial ...примарне сировине, минералогија, физичко-механичка својства, технолошка својства, наука о материјалимаDarko Bozovic, Vladimir Simic, Dragan Radulovic, Slobodan Radusinovic, Vesna Matovic, Anja Terzic. "Geochemical evaluation of dolostone deposits in Montenegro: Implications for potential industrial applications" in Science of Sintering, Bor, August 2024, National Library of Serbia (2024). https://doi.org/10.2298/SOS240701029B
-
Development Of The Serbian Geological Resources Portal
... concepts. The dictionary can also be searched with the use of key words. After entering a string of characters (word or part of a word), the user is offered a list of dictionary entries where the given string of characters appears, and by choosing from the list, the user can get a detailed view of the ...
... s to search and access the informa- tion they need. Thus geo-portals have an increasingly important role in the sharing of geologic information and can help avoid duplicated efforts, inconsistencies, delays, confusion, and a waste of resources. Development of the Serbian Geological Resources Portal ...
... creation of web applica- tions, offering the user a simple and intuitive interface with cross browser support. Conceptually, the con- tents of the portal can be divided into the part dedicat- ed to the cartographic presentation of spatial data, the multimedia part, and the active pages for database search ...Ranka Stanković, Jelena Prodanović, Olivera Kitanović, Velizar Nikolić. "Development Of The Serbian Geological Resources Portal" in Proceedings of the 17th Meeting of the Association of European Geological Societies, Belgrade, Serbia : The Serbian Geological Society (2011)
-
Classifying large strains from digital imagery: application to analogue models of lithosphere deformation
... view, displacementsat any given time refer to fixed locations in space, and not to specific material points. Byreconstructing the path of material, we can follow small regions of material while they translate,rotate and change shape. To aid the qualitative interpretation of this deformation, we have developed ...
... physically meaningful manner, but our method may be useful outside therealm of tectonics. Our software to compute deformation is freely available and can be used topost-process incremental displacements from PIV or similar autocorrelation methods. Powered by TCPDF (www.tcpdf.org) http://www.tcpdf.org ...Taco Broerse, Nemanja Krstekanić, Cor Kasbergen, Ernst Willingshofer. "Classifying large strains from digital imagery: application to analogue models of lithosphere deformation" in EGU General Assembly 2021, Vienna, Austria, 19.-30.4.2021., EGU (2021)
-
Turbidity simulation for short-term prediction: case study of the karst spring Surdup (Bor, Serbia)
Из перспективе снабдевања пијаћом водом, квалитет воде карстних издани је међу највишим, и често захтева само њихову дезинфекцију пре употребе. Међутим, карстне подземне воде изложене су одређеним притисцима. Током сушних периода углавном има мало воде, а током кишних периода има изненадних променa и квалитета и количине воде. Реакција слива на падавине је често брза и варијације у параметрима квалитета и квантитета (истицање, ниво вода, замућеност, укупан број микроорганизама, суспендовани нанос, итд.) су нестабилни. Ово захтева праћење истицања и ...Marina Pešić, Vesna Ristić Vakanjac, Boris Vakanjac, Kostadin Jovanov. "Turbidity simulation for short-term prediction: case study of the karst spring Surdup (Bor, Serbia)" in Comptes rendus de l'Academie bulgare des Sciences, Bulgarian academy of science (2016)
-
Laboratory testing of fly ash
Fly ash is one of the most common waste materials created by burning of coal. It is composed of smaller particles, consisting mainly of aluminosilicate glass, mullite and quartz, which are collected by electrostatic separators (filter) of gaseous products arising from the combustion of coal. This paper presents the pozzolanic properties, mechanical properties, chemical and mineral composition of fly ash obtained in the combustion process in a power plant Nikola Tesla A (PPNT A) with the addition of a ...chemical composition, fly ash, mechanical properties, mineral properties, pozzolanic properties, X-ray diffraction... to module R size, fly ash can be divided into: - silicate – calcium R < 2, - silicate R = 2 ÷ 6, - silicate – aluminum R > 6. 3. Classification of fly ash according to standard ASTM C – 618 from 1994 (ASTM C 618, 1994) Based on certain oxide content, fly ash can be divided into: Table ...
... research is to test the possibility of using the fly ash from PPNT A for making elements of road structures (top and bottom layers of the road). Fly ash can be used to create elements for road structures, but it must be taken into account that the embedding is done in segments, isolated from the influence ...
... Technical Gazette 23, 6(2016), 1839-1848 presence of certain phases in the system, the deformation of crystal lattice, the size of crystals. It can also be used for quantity analysis, or more precisely, for an estimation of different components share in the content of the sample [16]. All samples ...Miloš Šešlija, Aleksandra Rosić, Nebojša Radović, Milinko Vasić, Mitar Đogo, Milovan Jotić. "Laboratory testing of fly ash" in Tehnički vijesnik (2016). https://doi.org/10.17559/TV-20150317171035
-
Surface functional groups and degree of carbonization of selected chars from different processes and feedstock
Marija Ilić, Franz-Hubert Haegel, Aleksandar Lolić, Zoran Nedić, Tomislav Tosti, Ivana Sredović Ignjatović, Andreas Linden, Nicolai D. Jablonowski, Heinrich Hartmann (2022)The knowledge ofthe structural and chemical properties of biochars is decisive for their application as technical products. For this reason, methods for the characterization of biochars that are generally applicable and allow quality control are highly desired. Several methods that have shown potential in other studies were used to investigate two activated carbons and seven biochars from different processes and feedstock. The chars were chosen to cover a wide range of chemical composition and structural properties as a hardness ...Biougalj, različiti procesi dobijanja, različite sirovine, površinski aktivne grupe, x-ray, FT-IR,XPS... dielectric measurements can be in principle used for the determination of the conductivity and the degree of graphitization of carbon particles [15]. 'The low frequency impedance spectroscopy of rocks and soil is called spectral induced polari- zation (SIP) in geophysics. This method can be used to determine ...
... the van Krevelen diagram between AC1 and AC2 can be understood taking into account the presence of phosphoric acid in AC2 proven by ion chromatography. The differences in oxygen content between SW500f and HW500f as well as betveen HW1100g and PW700g can be explained by the extraordinarily high ash ...
... are optimized for producing designed chars. Biochar is a suitable basic material for the production of activated carbon [18-21]. Some- times it can also favorably substitute activated carbon with no or inexpensive modification due to lower costs [22,23] or improved properties [22]. It may show ...Marija Ilić, Franz-Hubert Haegel, Aleksandar Lolić, Zoran Nedić, Tomislav Tosti, Ivana Sredović Ignjatović, Andreas Linden, Nicolai D. Jablonowski, Heinrich Hartmann. "Surface functional groups and degree of carbonization of selected chars from different processes and feedstock" in PLOS ONE (2022). https://doi.org/10.1371/journal.pone.0277365