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326 items
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Određivanje sadržaja kiselih funkcionalnih grupa na površini biougljeva primenom Boehm-ovih titracija
Aleksandar D. Krstić, Aleksandar Đ. Lolić, Marija A. Ilić, Aleksandar M. Mijatović, Snežana J. Zlatanović, Zoran P. Nedić, Vesna M. Pavelkić (2015)Biougalj se dobija pirolizom iz organskog otpada. Smatra se ,,modifikatorom'' zemljišta i koristi se kao đubrivo i kao rezervoar za skladištenje ugljenika. Kvantifikacija funkcionalih grupa je važna zbog hemijske reaktivnosti biougljeva koji imaju uticaj na svojstva zemljišta. U istraživanju su korišćena 3 uzorka biouglja različitog porekla i jedan referentni, aktivni ugalj. Sadržaj kiselih funkcionalnih grupa je određivan titracijom po Boehm-u na dva načina: uvođenje N2 tokom titracije i tretman sa BaCl2. Optimizovan je način pripreme tri Boehm ova rastvora ...Aleksandar D. Krstić, Aleksandar Đ. Lolić, Marija A. Ilić, Aleksandar M. Mijatović, Snežana J. Zlatanović, Zoran P. Nedić, Vesna M. Pavelkić. "Određivanje sadržaja kiselih funkcionalnih grupa na površini biougljeva primenom Boehm-ovih titracija" in 52. savetovanja Srpskog hemijskog društva, Srpsko hemijsko društvo (2015) М64
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Uniaxial compressive strength test before and after standard fire test on rock mass
Stefan Mitrović, Goran Todorović, Bojan Kostić, Milica Mirković-Marjanović, Nikola Božović, Marija Krstić, Aleksandar Erić, Radovan Gospavić, Snežana Ilić, Aleksandar Kijanović (2022)Stefan Mitrović, Goran Todorović, Bojan Kostić, Milica Mirković-Marjanović, Nikola Božović, Marija Krstić, Aleksandar Erić, Radovan Gospavić, Snežana Ilić, Aleksandar Kijanović. "Uniaxial compressive strength test before and after standard fire test on rock mass" in Fifth symposium of the Macedonian Association for Geotechnics, Ohrid, North Macedonia, 23-25. 06. 2022, Macedonian Association for Geotechnics (2022) М33
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Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands
Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski (2023)Cancer remains one of the world's deadliest diseases, claiming many lives each day. Transition metal complexes are leading candidates in developing anticancer agens with cisplatin used in chemotherapy worldwide. Copper, an endogenous metal in the human body, is especially attractive because of its typical redox biological activities and a relatively strong affinity to nucleobases. A series of Cu(II) complexes with ethane-1,2-diamine as the amine part and pentane-2,4-dione and/or 1-phenylbutane-1,3-dione, pentane-2,4-dione and/or 1,1,1- trifluoropentane-2,4-dione, or 1,1,1-trifluoropentane-2,4-dione and/or 1-phenylbutane-1,3-dione as the ...Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski. "Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands" in Applied Organometallic Chemistry, Wiley (2023). https://doi.org/10.1002/aoc.7253 М21
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Distribution of major and trace elements in the Kovin lignite (Serbia)
Dragana Životić, Olga Cvetković, Predrag Vulić, Ivan Gržetić, Vladimir Simić, Konstantin Ilijević, Biljana Dojčinović, Suzana Erić, Bogdan Radić, Sanja Stojadinović, Snežana Trifunović (2019)geochemical and mineralogical study was performed on lignite samples from the Upper Miocene Kovin deposit, hosting three coal seams. The Kovin lignite is characterized by high moisture content, medium to high ash yield, medium to high sulphur content and a relatively low gross and net calorific value. The mineralogical composition, and major and trace element contents were determined by X-ray diffraction, scanning electron microscopy with energy dispersive Xray spectroscopy (SEM-EDS) analyses, and inductively coupled plasma optical emission spectrometry (ICP-OES). ...Dragana Životić, Olga Cvetković, Predrag Vulić, Ivan Gržetić, Vladimir Simić, Konstantin Ilijević, Biljana Dojčinović, Suzana Erić, Bogdan Radić, Sanja Stojadinović, Snežana Trifunović. "Distribution of major and trace elements in the Kovin lignite (Serbia)" in Geologia Croatica, Croatian Geological Survey (2019). https://doi.org/10.4154/gc.2019.06 М23
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188 М21
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557 М21