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Упит dcterms_creator_txt:Aleksandar D. Krstić

1268 items

  • Condition of the agricultural land use in the Danube riverside area with the aspect of their protection from high groundwater levels

    Pajić Predrag, Čalenić Aleksandar, Polomčić Dušan, Bajić Dragoljub (2018)

  • Sensitive Determination of Copper on New Modified Glassy Carbon Paste Electrode

    Škrivanj Sandra, Stanković M. Dalibor, Khan Muslim, Nikolić S. Aleksandar, Vulić Predrag, Manojlović D. Dragan (2015)

  • The state and perspective of the natural gas sector in Serbia

    Dejan Ivezić, Marija Živković, Dušan Danilović, Aleksandar Madžarević, Miloš Tanasijević (2016)
    The strategy of long-term energy development of Serbia identifies an increase of share of natural gas in final energy consumption as one of the main aims. Serbia has signed a strategic agreement with the Russian Federation on cooperation in the oil and gas sector, within which the project South Stream pipeline is planned to be realized. In addition, the Republic of Serbia has signed the Treaty that establishes the Energy Community and accepted the obligation to implement the Energy ...
    Consumption, natural gas, scenarios of development

  • Heterogeneity and Disorder in Ti1-xFeyO 2- d nanocrystal rutile-based flowerlike aggregates: Detection of anatase

    Kremenović Aleksandar, Antić Bratislav, Blanuša Jovan, Čomor Mirjana, Colomban Philippe, Mazerolles Leo, Božin Emil S. (2011)

  • Regionalno-geološke karakteristike miocenskih sedimenata na prostoru severnog Banata

    Dejan N. Radivojević (2014-12-30)
    Predmet doktorske disertacije predstavljalo je rešavanje strukturno‐stratigrafskihodnosa miocenskih sedimenata na prostoru severnog Banata. U cilju regionalnogsagledavanja, korišćeni su svi raspoloživi geofizički i geološki podaci sa širegistražnog područja, odnosno iz celog Panonskog basena i susednog orogena. Osimklasičnih metoda primenjene su i savremene metode seizmostratigrafije,tektonostratigrafije i riftne sekvencione stratigrafije. Primenjene metode omogućilesu izradu modela progradacije ivice šelfa za ceo Panonski basen, modela uzajamnihveza između basena i geodinamičkog modela jugoistočnog oboda basena.Jezero Panon je većim delom zapunjeno prilivom sedimenata paleo‐Dunavom saseverozapada, odnosno ...
    Centralni Paratetis, Panonski basen, miocen, jezero Panon,seizmostratigrafija, sekvenciona stratigrafija, paleogeografija, geodinamika
    ... HZRDBgHSfDObG ZR D BgH SfD ZR D SkH ZR D BgH SfD PcD ZR D BgH SfD ZR D SkH ZR D BgH SfD PcD ZR D BgH SfD ZR D SkH ZR D BgH SfD D rD ZRDBgHSfDZRDSkHZRDBgHSfDBCH G jH ZgD ZR D BgH SfD ZR D SkH ZR D BgH SfD PnD ZR D Bg H Sf D ZR D Sk H ZR D Bg H Sf D Ss D ShG Kontakt Zapadni ...
    ... Prosodacna sp. /P. cf. Vodopici/, Monodacna simplex, Caladacna steindachneri, Dreissena sabbae, D. cf. cucullata, D. rostriformis, D. minima, D. superfoetat, D. auricularis, D. auricularis simplex, Dreissenomya digitifera, Pisidium protractrum, Plagiodacna auingeri) i puževa (Gyraulus ...
    ... FRUŠKA GORA PLANINE VRŠAČKE/VĂRADIA BUKULJA D I N A R I D I A P U S E N I J U Ž N I K A R P A T I CER Bukovac PlH MkD AyH TcD S C D K M H B A D BkD SzD Kk D VIH CnD BjH BT D TcH OhH BM DBRH BBH SMH SrD SrD TrH TrD ...

  • A Twitter Corpus and Lexicon for Abusive Speech Detection in Serbian

    Danka Jokić, Ranka Stanković, Cvetana Krstev, Branislava Šandrih (2021)
    Uvredljivi govor na društvenim medijima, uključujući psovke, pogrdni govor i govor mržnje, dostigao je nivo pandemije. Sistem koji bi bio u stanju da detektuje takve tekstove mogao bi da pomogne da internet i društveni mediji postanu bolji virtuelni prostor sa više poštovanja. Istraživanja i komercijalna primena u ovoj oblasti do sada su bili fokusirani uglavnom na engleski jezik. Ovaj rad predstavlja rad na izgradnji AbCoSER-a, prvog korpusa uvredljivog govora na srpskom jeziku. Korpus se sastoji od 6.436 ručno označenih ...
    uvredljivi jezik, govor mržnje, srpski, tviter, leksikon, korpus
    ... pdf https://www.aclweb.org/anthology/2020.globalex-1.1.pdf 13:16 Building Language Resources for Abusive Language Detection in Serbian 19 Ivana Krstić. Report on the use of hate speech in Serbian media, 2020. URL: https: //rm.coe.int/hf25-hate-speech-serbian-media-eng/1680a2278e. 20 K. Kumaresan ...
    ... excerpt from RDF version with frequency and attestations. # subproperty d e f i n i t i o n f o r f requency in t w i t t e r corpus : atv itkoFrequency r d f s : subClassOf f r a c : CorpusFrequency . : atv itkoFrequency r d f s : subClassOf [ a owl : R e s t r i c t i o n ; owl : onProperty f r a ...
    ... ex : s ense : lopov−s ense . : lopov−form a onto l ex : Form ; onto l ex : writtenRep " lopov " @sr . : lopov−s ense skos : d e f i n i t i o n " onaj k o j i krade , k r a d l j i v a c , lupe ž ; otima č , p l j a čka š ; prevarant , lupe ž " @sr ; onto l ex : r e f e r e n c e

  • Age and microfacies of oceanic Upper Triassic radiolarite components from the Middle Jurassic ophiolitic mélange in the Zlatibor Mountains (Inner Dinarides, Serbia) and their provenance

    Hans-Juergen Gawlick, Nevenka Đerić, Sigrid Missoni, Nikita Bragin, Milan Sudar, Divna Jovanović (2017)
    Neo-Tethys, trench-like basins, synorogenic deposition, evolving thrust belt, Triassic palaeogeography
    ... Qucen Charlotte Islands, British Columbia, Canada. Mećmoires de Gćologie (Lausanne) 11, 1—175. Chiari M., Djerić N., Garfagnoli F., Hrvatović H., Krstić M., Levi N., Malasoma A., Marroni M., Menna F., Nirta G., Pandolfi L., Principi G., Saccani E., Stojadinović U. & Trivić B. 2011: The Geology ...
    ... S., Suzuki H., Sudar M., Lein R. & Jovanović D. 2016b: Triassic radiolarite and carbonate components from the Jurassic ophiolitic mćlange (Dinaridic Ophiolite Belt). Swiss J. Geosci. 109, 3, 473-494, Goričan Š., Karamata S. & Batočanin-Srećković D. 1999: Upper "Triassic (Carnian- Norian) ra ...
    ... wackestone to packstone in a muddy and only slightly slicificd matrix. All radiolarians are preserved as microquartz. Sample SCG 51, Scale bar=1 mm. d — Completely slicificd greyish radiolarite. The radiolarians occur as microquartz and are visible only as ghosts in the thin section. The preservation ...

  • Natural two-dimensional pyrophyllite: Nanoscale lubricant, electrical insulator and easily-machinable material

    Borislav Vasić, Radoš Gajić, Ivana Milošević, Žarko Medić, Marina Blagojev, Marko Opačić, Aleksandar Kremenović, Dejan Lazić (2022)
    Pyrophyllite, with the chemical formula Al2Si4O10(OH)2, is a naturally occurring and abundant van der Waals mineral belonging to the group of phyllosilicates. It is very soft, layered crystal used for sculpting and an excellent electrical and thermal insulator aimed for the operation at high pressure and temperature. Here, for the first time, two-dimensional (2D) pyrophyllite obtained by both mechanical and liquid phase exfoliation is presented and investigated at the nanoscale. The layered structure provides low friction coefficient of around ...
    Atomic force microscopy, Insulating properties, Nanofriction and wear, Natural two dimensional materials, Phyllosilicates, Pyrophyllite

  • A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)

    Gordana Gajica, Aleksandra Šajnović, Ksenija Stojanović, Jan Schwarzbauer, Aleksandar Kostić, Branimir Jovančićević (2021)
    The molecular and isotopic composition of biomarkers in initial bitumen isolated from immature (0.41% Rr) oil shale samples (Aleksinac deposit) and liquid products obtained by pyrolysis in open (OS) and closed (CS) systems are studied. The influence of pyrolysis type and variations of kerogen type on biomarkers composition and their isotopic signatures in liquid products is determined. The applicability of pyrolysis type, numerous biomarkers and carbon isotopic compositions (δ13C) of n-alkanes in liquid pyrolysates is established. Pyrolysis experiments were ...
    Uljni šejl, Aleksinac, organska supstanca, otvoreni i zatvoreni sistem pirolize, biomarkeri, izotopski sastav ugljjenika

  • Стање квалитета амбијенталног ваздуха на подручју града Панчева

    Александар Маринковић (2024)
    Квалитет ваздуха је кључни фактор за здравље људи и очување животне средине. У овом завршном раду анализирано је стање амбијенталног ваздуха на територији града Панчева како би се сагледали извори загађења, ПЛН мониторинга и изазови у погледу квалитета ваздуха са којима се суочавају сви становници. Кроз примену савремених метода праћења, идентификовани су главни извори загађења и анализирана је дистрибуција загађујућих материја у урбаном окружењу.Праћењем концентрације загађивача као што су честице PM10, PM2.5, сумпор-диоксид (SO2), азот-диоксид (NO2) и други, ...
    мониторинг, загађивачи, здравље, Панчево, квалитет ваздуха
    ... квалитета амбијенталног ваздуха на подручју града Панчева Александар Маринковић Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Стање квалитета амбијенталног ваздуха на подручју града Панчева | Александар Маринковић | | 2024 | | http://dr.rgf.bg.ac.rs/s/repo ...
    ... 1-uacoOBHa KOHLeHTpaL\Mja npg3eMHOr O3OHa 3a 2023. ronMHy 180 ? o 160 | pj Ž 140 š F3 120 H ii 100 [ ... 80 = -i 60 o | | d 40 EI d 20 o = 0 OJ ngg) @@ć QQ•X“\\ Ž „ t — “ Ć ?g)* m Average of BarporacHM > OM Meceun p— Average of Uapa JlyuiaHa Cnuka &8.3.2 Makcuanna 1-uacoena ...
    ... 2023. ronMHy [u] 100 r i 90 o 80 Fi 70 š 60 : % 50 i 40 š_ 30 š 20 T 10 EI ŠO e K & „S . 3 . & & ı . = ~ r @'DQ (\Q{\ “ . r O – d O m a Average of Lllapa R\yuiaHa Meceua mm— Average of BarporacHM nOM Cauka 8.3.1 MakcuanHa 24-uacoeHa koHueHmpauuja npu3eMHoo o3oHa 3a 2023. ...

  • Pleistocene rhinoceros from Bogovina Cave: the first report of Stephanorhinus hundsheimensis Toula, 1902 (Mammalia, Rhinocerotidae) from Serbia

    Predrag Radović, Miloš Radonjić, Emmanuel Billia (2020)
    Finds of Pleistocene rhinoceros are rare in Serbia, and only one species (the woolly rhinoceros Coelodonta antiquitatis Blumenbach, 1799) has been reported so far. The current paper presents the dental material of an extinct so-called Hundsheim rhinoceros, Stephanorhinus hundsheimensis Toula, 1902 from Bogovina Cave (East ern Serbia). Both the morphological and metric characteristics of the teeth are consis tent with the attribution to S. hundsheimensis. Unfortunately, the rhinoceros material originated from an uncertain geological context, so there is no ...
    rhinoceros, Stephanorhinus hundsheimensis, Serbia
    ... Pleistoceno de El Baradello, Plaça de la República y El Molinar en Alcoy, España. Recerques del Museu d’Alcoi, 16:7-18. Veselinović, M., Antonijević, I., Krstić, B., Mićić, I., Milošaković, R., Rakić, B., and Banković, V., 1964. Osnovna geološka karta SFRJ 1:100000 - list Boljevac. Savezni geološki zavod, ...
    ... lingual, (D) mesial and (E) distal views; right P3/P4 HMP-139b in (F) occlusal, (G) lingual, and (H) distal views. PALAEO-ELECTRONICA.ORG 5 FIGURE 4. Upper molars of Stephanorhinus hundsheimensis from Bogovina Cave: right M1/M2 HMP-131 in (A) occlu- sal, (B) vestibular, (C) lingual, (D) mesial and ...
    ... dell’Istituto Geologico dell’Università di Pavia, 20:67-81. Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Rüther, P.L., Fotakis, A.K., Lyon, D., Moreno-Mayar, V.J., Bukhsianidze, M., Jersie-Christensen, R.R., Mackie, M., Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou ...

  • The influence of alkyl polyglucosides (and highly ethoxylated alcohol boosters) on the phase behavior of a water/toluene/technical alkyl polyethoxylate microemulsion system

    Marija Ilic, Franz-Hubert Haegel, Vesna Pavelkic, Dragan Zlatanovic, Snezana Nikolic-Mandic, Aleksandar Lolic, Zoran Nedic (2016)
    The influence of additives (alkyl polyglucoside, Glucopon 600 CS UP and alcohol ethoxylate C18E100) on the behavior of the water/toluene/Lutensol ON 50 (technical oxoalcohol, i-C10E5) microemulsion system as a function of temperature and composition has been investigated. The phase behavior of the microemulsions was determined by vertical sections through the Gibbs phase prism (fish-like phase diagrams). Alkyl polyglucoside shifts the one phase region to lower temperatures compared with water/toluene/Lutensol ON 50 mixtures. This is contrary to the expectation, considering ...
    микроемулзија, толуен, алкил полиглукозид, оксоалкохол етоксилат, појачивач ефикасности, „fish“ дијаграми
    ... ZLATANOVIĆ“ SNEŽANA NIKOLIĆ-MANDIĆS ALEKSANDAR LOLIĆS ZORAN NEDIĆS [29] [30] [31] [32] W.C. Griffin, J. Soc. Cosmet. Chem. 1(5) (1949) 311-326 M. Kahlweit, R. Strey, Angew. Chem. Int. Ed. Engl. 24 (1985) 654-668 M. Kahlweit, R. Strey, P. Firman, D. Haase, Langmuir 1 (1985) 281-288 ...
    ... echnical alkyl polyethoxylate microemulsion system Marija Ilic, Franz-Hubert Haegel, Vesna Pavelkic, Dragan Zlatanovic, Snezana Nikolic-Mandic, Aleksandar Lolic, Zoran Nedic Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] The influence of alkyl polyglucosides ...
    ... chnical alkyl polyethoxylate microemulsion system | Marija Ilic, Franz-Hubert Haegel, Vesna Pavelkic, Dragan Zlatanovic, Snezana Nikolic-Mandic, Aleksandar Lolic, Zoran Nedic | Chemical Industry and Chemical Engineering Quarterly | 2016 | | 10.2298/CICEQ141105015I http://dr.rgf.bg.ac.rs/s/repo/item/0008425 ...

  • The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector

    Aleksandar R. Madžarević, Dejan D. Ivezić, Miloš L. Tanasijević, Marija A. Živković (2020)
    Natural gas is used for the production of almost 20% of total energy today. The natural gas security of the Republic of Serbia is an urgent strategic, political and security issue. Serbia is one of the most vulnerable countries in Southeast Europe, because it only has one supply route. This study is a contribution to efforts to better understand the factors affecting energy security through the implementation of a new methodology based on the fuzzy–AHP synthesis model for measuring ...
    energetska bezbednost, prirodni gas, fazi AHP, AHP višekriterijumska analiza, fazi teorija
    ... Sector Aleksandar R. Madžarević, Dejan D. Ivezić, Miloš L. Tanasijević, Marija A. Živković Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector | Aleksandar R. Madžarević ...
    ... rgf.bg.ac.rs symmetryS S Article The Fuzzy–AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector Aleksandar R. Madžarević *, Dejan D. Ivezić, Miloš L. Tanasijević and Marija A. Živković Faculty of Mining and Geology, University of Belgrade, Djusina 7, 11000 Belgrade ...
    ... mmetry se symmetry (mort, Article The Fuzzy—AHP Synthesis Model for Energy Security Assessment of the Serbian Natural Gas Sector Aleksandar R. MadiZarevié *, Dejan D. Ivezié, Milos L. Tanasijevié® and Marija A. Zivkovié Faculty of Mining and Geology, University of Belgrade, Djusina 7, 11000 Belgrade ...

  • Kinetics, mechanism, and equilibrium studies of the reactions between a ruthenium(II) complex and some nitrogen- and sulfur-donor nucleophiles

    Aleksandar M. Mijatović, Ratomir M. Jelić, Jovana Bogojeski, Živadin D. Bugarčić, Biljana Petrović (2013)
    Kinetika i mehanizam reakcija supstitucije između [Ru(trpi)(bpi)Cl]+ sa nukleofilima gvanozin-5′-monofosfatom, L-histidinom, tioureom i dimetilsulfoksidom proučavani su spektrofotometrijski u 0,1 M NaClO4 na 310 K. Red reaktivnosti za odabrane ligande je: tiourea > gvanozin-5′-monofosfat > L-histidin > DMSO. Ovaj red je povezan sa elektronskim, strukturnim i hemijskim karakteristikama kompleksa i nukleofila. Reakcija supstitucije sa tioureom je proučavana na tri različite temperature (288, 298 i 310 K). Negativna entropija aktivacije DS = potvrđuje asocijativni način aktivacije. Formiranje kompleksa [Ru(trpi)(bpi)H2O]2+ sa ligandima ...
    Kinetika, Ravnoteža, Ru(II), L-Histidin, Guanozin-5' -monofosfat, Dimetilsulfoksid, Tiourea
    ... equilibrium studies of the reactions between a ruthenium(II) complex and some nitrogen- and sulfur-donor nucleophiles Aleksandar M. Mijatović, Ratomir M. Jelić, Jovana Bogojeski, Živadin D. Bugarčić, Biljana Petrović Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] ...
    ... equilibrium studies of the reactions between a ruthenium(II) complex and some nitrogen- and sulfur-donor nucleophiles | Aleksandar M. Mijatović, Ratomir M. Jelić, Jovana Bogojeski, Živadin D. Bugarčić, Biljana Petrović | Monatshefte für Chemie - Chemical Monthly | 2013 | | 10.1007/s00706-013-1044-1 http://dr ...
    ... equilibrium studies of the reactions between a ruthenium(II) complex and some nitrogen- and sulfur- donor nucleophiles Aleksandar M. Mijatović • Ratomir M. Jelić • Jovana Bogojeski • Živadin D. Bugarčić • Biljana Petrović Received: 27 March 2013 / Accepted: 25 June 2013 / Published online: 22 August ...

  • Efekti potencijalnog korišćenja postrojenja za preradu otpadnih voda kao energetskih izvora u sistemima daljinskog grejanja u Srbiji

    Dejan Ivezić, Marija Živković, Aleksandar Madžarević (2019)
    Системи даљинског грејања постоје у 57 градова и општина у Србији и доминантно користе фосилна горива. У овим урбаним срединама су изграђени, или се планира градња система за пречишћавање отпадних вода. У раду је размотрена (са еколошког и енергетског аспекта) могућност додатног, енергетског коришћења топлоте пречишћене воде у СДГ, применом топлотних пумпи. На примеру Шапца је извршено поређење постојећег СДГ са системом који би применом топлотних пумпи искористио енергетски потенцијал система за пречишћавање отпадних вода. Добијени индикатори су послужили ...
    системи даљинског грејањa, постројења за пречишћавање отпадних вода, топлотне пумпе
    ... Živković, Aleksandar Madžarević Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Efekti potencijalnog korišćenja postrojenja za preradu otpadnih voda kao energetskih izvora u sistemima daljinskog grejanja u Srbiji | Dejan Ivezić, Marija Živković, Aleksandar Madžarević ...
    ... пречишћавања отпадних вода су приказане на слици 4. 0 10 20 30 40 50 60 0 500 1000 1500 2000 2500 3000 3500 h e a t lo a d f o r D H g ri d i n M W hours per year 91 | Стручно научна конференција ТОПС 2019 Слика 4 Просечна месечна температура пречишћене воде ...
    ... КОРИШЋЕЊА ПОСТРОЈЕЊА ЗА ПРЕРАДУ ОТПАДНИХ ВОДА КАО ЕНЕРГЕТСКИХ ИЗВОРА У СИСТЕМИМА ДАЉИНСКОГ ГРЕЈАЊА У СРБИЈИ Дејан Ивезић, Марија Живковић, Александар Маџаревић Универзитет у Београду, Рударско-геолошки факултет, Београд, Србија dejan.ivezic@rgf.bg.ac.rs, marija.zivkovic@rgf.bg.ac.rs, aleksandar ...

  • Directions of future geological explorations of mineral resources in Serbia

    Jelenković Rade, Simić Vladimir, Kostić Aleksandar, Životić Dragana, Tošović Radule (2016)

  • BaTiO3/NixZn1−xFe2O4 (x = 0, 0.5, 1) Composites Synthesized by Thermal Decomposition: Magnetic, Dielectric and Ferroelectric Properties

    Marija Šuljagić, Ivan Petronijević, Miljana M. Mirković, Aleksandar Kremenović, Adis Džunuzović, Vladimir B. Pavlović, Aleksandra Kalezić-Glišović, Ljubica Andjelković (2023)
    To investigate the influence of spinel structure and sintering temperature on the functional properties of BaTiO3/NixZn1−xFe2O4 (x = 0, 0.5, 1), NiFe2O4, ZnFe2O4, and Ni0.5Zn0.5Fe2O4 were in situ prepared by thermal decomposition onto BaTiO3 surface from acetylacetonate precursors. As-prepared powders were additionally sintered at 1150 °C and 1300 °C. X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS) were used for the detailed examination of phase composition and morphology. The magnetic, dielectric, and ...
    ferroelectric, dielectric properties, magnetic properties, titanate/ferrite composites, phase composition
    ... Synthesized by Thermal Decomposition: Magnetic, Dielectric and Ferroelectric Properties Marija Šuljagić, Ivan Petronijević, Miljana M. Mirković, Aleksandar Kremenović, Adis Džunuzović, Vladimir B. Pavlović, Aleksandra Kalezić-Glišović, Ljubica Andjelković Дигитални репозиторијум Рударско-геолошког ...
    ... Synthesized by Thermal Decomposition: Magnetic, Dielectric and Ferroelectric Properties | Marija Šuljagić, Ivan Petronijević, Miljana M. Mirković, Aleksandar Kremenović, Adis Džunuzović, Vladimir B. Pavlović, Aleksandra Kalezić-Glišović, Ljubica Andjelković | Inorganics | 2023 | | 10.3390/inorganics11020051 ...
    ... by Thermal Decomposition: Magnetic, Dielectric and Ferroelectric Properties Marija Šuljagić 105, Ivan Petronijević ?, Miljana M. Mirković 36), Aleksandar Kremenović 5, Adis Džunuzović 5, 5 Vladimir B. Pavlović , Aleksandra Kalezić-Glišović 72 and Ljubica Andjelković +G Q check for updates Citation: ...

  • Equilibrium and kinetic studies of the reactions between [Ru(terpy)(bipy)Cl]Cl complex and biologically important N-donor ligands

    Aleksandar Mijatović, Biljana Petrović, Ratomir Jelić, Živadin Bugarčić (2011)
    Studije u oblasti antikancerogenih karakteristika jedinjenja rutenijuma(III/II) izazivaju veliku pažnju već nekoliko godina otkako su neka od njih kao što su KP1019 (indazolijum-tetrahloridobis(H-indazol)rutenat(III)) i NAMI-A (imidazolijum) -trans-tetrahlorido(dimetilsulfoksid)indazolerutenat(III)) dostigao nivo kliničkog ispitivanja. Kompleksi rutenijuma u ​​reakciji sa molekulom DNK formiraju prvenstveno gvanin- i adenin-adukt, kao komplekse platine. Takođe, nekoliko studija ukazuje na veoma jake interakcije sa proteinima. Međutim, kompleksi Ru(III/II) pokazuju generalno manje toksične efekte od lekova platine(II).1 Proučavali smo kinetiku reakcija supstitucije kompleksa [Ru(terpi)(bipi)Cl]Cl sa biološki važnim ligandima: dimetilsulfoksidom, gvanozin-5’-monofosfatom, ...

  • Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals

    Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić (2020)
    As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcumin was used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: ...
    nanocrystal, curcumin, top-down method, wetball milling

  • Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study

    Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)
    Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...
    Pharmaceutical Science
    ... study Jelena R. Mitrović*, Maja Bjelošević Žiberna b, Aleksandar Vukadinović", Daniel E. Knutson d, Dishary Sharmin d, Aleksandar Kremenović *, Pegi Ahlin Grabnar , Odon Planinšek , Dominique Lunter', James M. Cook “, Miroslav M. Savić”, Snežana D. Savić “ * Department of Pharmaceutical Technology ...
    ... stability study Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić Дигитални репозиторијум Рударско-геолошког факултета ...
    ... stability study | Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić | European Journal of Pharmaceutical Sciences | 2023 ...