Претрага
251 items
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... with a cooling rate of 40 ◦C/min and finally heated again to 330 ◦C with a heating rate of 10 ◦C/min. The measurements were conducted under nitrogen flow (50 mL/min) by DSC 1 (Mettler-Toledo AG, Analytical, Greifensee, Switzerland). The onset and peak temperature, and enthalpy were evaluated by STAR® ...
... heated to 330 ◦C in aluminum pans with a heating rate of 10 ◦C/min using DSC 1 (Mettler-Toledo AG, Analytical, Greifensee, Switzerland). The nitrogen flow during the measurements was set to 50 mL/min. X-ray Powder Diffraction Analysis (XRPD) Nanocrystal dispersions with different particle sizes, cor ...
... XTerra MS C18 column (150 × 2.1 mm, 3.5 µm particle size). The mobile phase containing acetonitrile and 0.1% formic acid (50:50, v/v) was eluated at the flow rate of 0.3 mL/min. The column tempera- ture was set to 35 ◦C. Detection and quantification of DK-I-60-3 and internal standard were performed in positive ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Atmospheric exposure vs burying: influences on damage intensity of built-in kersantite in the monument of the Small Staircase (Belgrade, Serbia)
Proučavan je efekat „zatrpanog kamena“ na intenzitet procesa degradacije prisutnih na kersantitu koji je ugrađen u spomenik Malo stepenište. Istraživanja su vršena na uzorcima stene iz kamenoloma i na oštećenim kamenim blokovima ugrađenim u spomenik. Dok su neki delovi stepeništa bili pod zemljom 90 godina, većina kamenih elemenata je bila izložena različitim uslovima sredine i antropogenim uticajima. Urađeno je detaljno mapiranje trenutnog stanja spomenika kako bi se istražio uticaj “zatrpavanja” i kompleksne geometrije spomenika na tip propadanja i variranje ...Nevenka Novaković, Predrag Dabić, Vesna Matović. "Atmospheric exposure vs burying: influences on damage intensity of built-in kersantite in the monument of the Small Staircase (Belgrade, Serbia)" in Environmental Earth Sciences, Springer Science and Business Media LLC (2023). https://doi.org/10.1007/s12665-023-10794-6
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Analiza rada električnih centrifugalnih pumpi
Milica Stanojević (2024)Ovaj rad analizira rad električne centrifugalne pumpe (ESP) u naftnoj industriji, sa fokusom na problem taloženja kamenca (karbonatnih naslaga) unutar sistema. Električne centrifugalne pumpe (ESP) predstavljaju srce mnogih naftnih bušotina. Njihova visoka pouzdanost i sposobnost rada u zahtevnim uslovima čine ih neophodnim za stabilnu i kontinuiranu proizvodnju.Senzori igraju ključnu ulogu u praćenju rada ESP sistema i detekciji ranih znakova taloženja kamenca. Problem taloženja kamenca je izuzetno značajan, jer može dovesti do smanjenja efikasnosti pumpe, povećanja troškova održavanja, i dugoročnih zastoja ...... U takvim slučajevima, senzori protoka mogu automatski pokrenuti alarme ili čak isključiti pumpu kako bi se sprečilo oštećenje (SLB, "Stratified Flow," n.d.). 27 Analiza rada električnih centifugalnih pumpi 4.5 SCADA sistem Nadzorna kontrola i prikupljanje podataka (SCADA) je važan kompjuterski ...
... temperature_survey 20.SLB, „Jibratory Seismic Dana“, n.d. URL: https://glossary.slb.com/en/terms/v/vibratory_seismic_data 21.SLB, „„tratified Flow," n.d. URL: https://glossary.slb.com/en/terms/s/stratified_flow 22.Almalawi, A., Tari, Z., Fahad, A., Yi, X., 2021. „SCADA SECURITY: Machine Learning ...Milica Stanojević . Analiza rada električnih centrifugalnih pumpi, 2024
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Machine learning based landslide assessment of the Belgrade metropolitan area: Pixel resolution effects and a cross-scaling concept
Improvements of Machine Learning-based landslide prediction models can be made by optimizing scale, customizing training samples to provide sets with the best examples, feature selection, etc. Herein, a novel approach, named Cross-Scaling, is proposed that includes the mixing of training and testing set resolutions. Hypothetically, training on a coarser resolution dataset and testing the model on a finer resolution should help the algorithm to better generalize ambiguous examples of landslide classes and yield fewer over/underestimations in the model. This ...Uroš Đurić, Miloš Marjanović, Zoran Radić, Biljana Abolmasov. " Machine learning based landslide assessment of the Belgrade metropolitan area: Pixel resolution effects and a cross-scaling concept" in Engineering Geology , Elsevier (2019). https://doi.org/10.1016/j.enggeo.2019.05.007
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Stratigraphic implications of the Mio-Pliocene geodynamics in the area of Mt. Avala: new evidence from Torlak Hill and Beli Potok (Belgrade, Serbia)
Mt. Avala is located on the southern margin of the Pannonian basin (SPB), a border zone between the uplifted morphostructures of the Dinarides and Carpathian-Balkanides. Similar to the Pannonian basin, tectonostratigraphic evolution of the Mt. Avala area during the last 23 Ma has is characterized by syn- and post-rifting processes as well as tectonic inversion. Here, we present the results of field investigations of the Miocene‒Pliocene dynamics that led to different spatial positions of the same stratigraphic units (e.g. ...... as the uplift of Torlak Hill progressed, the Zavojnička Reka changes its flow from SE-NW and turns to- wards the E-NE, away from Torlak. This activity led to the for- mation of the new, local structure along which the new flow was established (Fig. 21). The Beli Potok trough is situated between these ...
... formed by movements along the Rakovica fault system (RF) and the Torlak fault (Fig. 20). In respect of the geomorphologic properties of the unusual flow/geometry of the Zavojnička Reka near the Torlak block, we don’t have documented data. But, based on some observations by MAROVIĆ & KNEŽEVIĆ (1985) ...Ljupko Rundić, Meri Ganić, Slobodan Knežević, Dejan Radivojević, Miloš Radonjić. "Stratigraphic implications of the Mio-Pliocene geodynamics in the area of Mt. Avala: new evidence from Torlak Hill and Beli Potok (Belgrade, Serbia)" in Geologia Croatica (2019). https://doi.org/10.4154/gc.2019.11
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Heavy metals in lignite and soil of Kostolac-Kovin coal basin, eastern Serbia - comparative analysis with selected cities in Serbia, region, Europe and world
Bogoljub Vučković, Bojan Dimitrijević (2023)The Kostolac-Kovin coal basin with an area of 320 km2, with 5 separate layers of coal and with a total of about 5.7 Bt of geological resources and reserves represents an exceptional potential for coal production in Serbia. The coal resources listed in this way are not fully exploitable, but they represent potential for consideration. In this paper, we deal with the geochemical characteristics of coal seams and perform a comparative analysis of coal affectation on the environment. With ...... heavy metals, concentrations 1. GENERAL INFORMATIONS The coal basin is located in castern Serbia, between the Velika Morava and Mlava rivers, which flow into the Danube in that area (figure 1 and 2). Itis divided into two parts by the Danube - to the south is the Kostolac Basin, and to the north ...Bogoljub Vučković, Bojan Dimitrijević. "Heavy metals in lignite and soil of Kostolac-Kovin coal basin, eastern Serbia - comparative analysis with selected cities in Serbia, region, Europe and world" in 9th International Conference Mining and Environmental Protection, 24–27. May 2023, Sokobanja, Beograd : Univerzitet u Beogradu, Rudarsko-geološki fakultet (2023)
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Hydrographic and hydrological characterization of the Vodenička and Rosomačka rivers
Vesna Ristić Vakanjac, Marina Čokorilo Ilić, Dušan Polomčić, Dragoljub Bajić, Jelena Ratković (2017)The Visočica River rises in Bulgaria, on the Berovo Mountain. Its course in Bulgaria is 16.7 km long. It enters Serbia near the village of Donji Krivodol. Up to the village of Pakleštica, or the beginning of Lake Zavoj, its right-bank tributaries are the Krivodolštica, the Vodenička, the Rosomačka and the Dojkinačka. There are no left-bank tributaries. Among the tributaries, water levels and discharges are gauged only on the Dojkinačka River. The Vodenička had also been gauged but only ...... junction of the Caričin Creek and the Zanoška River. It empties into the Visočica River at 724 m.a.s.l., near the village of Slavinja. The general flow direction is north-to-south and the catchment is between the watersheds of the Jelovica River, which is the main right-bank tributary of the Dojkinačka ...
... union of the Jelov Dol and the Studena Bara. It empties into the Visočica between the villages of Izatovac and Braćevci, at 755 m.a.s.l. The general flow direction is north-to-south and the catchment is between those of the Rosomačka (west) and the Krivodolštica (east). A water divide separates it from ...Vesna Ristić Vakanjac, Marina Čokorilo Ilić, Dušan Polomčić, Dragoljub Bajić, Jelena Ratković. "Hydrographic and hydrological characterization of the Vodenička and Rosomačka rivers" in Pirotski zbornik, Pirot : Narodna biblioteka Pirot (2017). https://doi.org/10.5937/pirotzbor1742001R
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VENTEX: An Expert System for Mine Ventilation Systems Analysis
Analiza sistema za ventilaciju je komleksan proces, koji bazira na proračunu brojnih parametara, koji se odnose na: stanje mreže, provetrenost, stabilnost sistema, gubitke vazduha, klimatske uslove, gasno stanje, ugroženost od požara i opasne prašine. Navedeni problemi se uspešno rešavaju paketom SimVent, ali potpuno razumevanje i korišćenje dobijenih rezultata zahteva angažovanje iskusnog specijaliste iz oblasti ventilacije. Rešenje je nađeno u kreiranju ekspertnog sistema VENTEX, čija je baza znanja formalizacija ekspertskog znanja iz oblasti ventilacije rudnika. U radu je prikazana metodologija ...... of Mining and Geology of the University of Belgrade (Lilić, Stanković, and Obradović, 1994). This package, which enables the simulation of air flow distribution in a mine, the heat and fire transmission mechanisms, distribution of gas and distribution of respirable mineral dust, is currently ...Ranka Stanković, Nikola Lilić, Ivan Obradović. "VENTEX: An Expert System for Mine Ventilation Systems Analysis" in YU Info '96 Brezovica, Društvo za informacione sisteme i računarske mreže (1996)
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GNSS Time Series as a Tool for Seismic Activity Analysis Related to Infrastructure Utilities
Sanja Tucikešić, Ankica Milinković, Branko Božić, Ivana Vasiljević, Mladen Slijepčević . "GNSS Time Series as a Tool for Seismic Activity Analysis Related to Infrastructure Utilities" in Contributions to International Conferences on Engineering Surveying. Springer Proceedings in Earth and Environmental Sciences, Dubrovnik, Croatia, October 22-23, 2020, Springer, Cham (2021). https://doi.org/10.1007/978-3-030-51953-7_21
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Improvement of education through the cooperation between CEEPUS EURO Geo-Sci network and scientific projects: examples from UB-FMG
Kristina Šarić, Dejan Prelević, Miloš Marjanović, Uroš Stojadinović, Vladimir Simić . "Improvement of education through the cooperation between CEEPUS EURO Geo-Sci network and scientific projects: examples from UB-FMG" in V Congress of Geologists of Republic of Macedonia ": “Geology in a changing world”, Makedonsko geološko društvo (2024)
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Hibridni sistem za planiranje i analizu ventilacije rudnika
... MODELING OF AIR FLOW PROCESSES IN MINE CHAMBERS USING COMPUTATIONAL FLUID DYNAMICS Theoretical Foundations of Computational Fluid Dynamics………………………….43 What is CFD ? General Form of the Balance Equation Initial and Boundary Conditions State Equations Laminar and Turbulent Flow Reynold’s Equations ...
... Package for Defining Aerodynamic Resistance Distribution in Complex Mine Ventilation Networks…………………...130 CHAPTER 5 MODELING OF AIR FLOW DISTRIBUTION Air Flow Distribution…………………………………………………………………..……139 Ventilation Network Laws Natural Air Distribution 339 O knjizi1 Metodologija planiranja ...
... the book Planing of required air flow quantities INVENTS ResNet SimVent VENTEX defining basic netw ork resistance ventilation system estimation ventilation simulation Design CFD Estimates estimation of gas and dust emission and temperature conditions flow process modelling using CFD Data ...Nikola Lilić, Ranka Stanković, Ivan Obradović. Hibridni sistem za planiranje i analizu ventilacije rudnika, Rudarsko-geološki fakultet, Univerzitet u Beogradu, 2000
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An arid phase in the Internal Dinarides during the early to middle Miocene: Inferences from Mg-clays in the Pranjani Basin (Serbia)
N. Andrić-Tomašević, V. Simić, O. Mandic, D. Životić, M. Suárez, E. García-Romero. "An arid phase in the Internal Dinarides during the early to middle Miocene: Inferences from Mg-clays in the Pranjani Basin (Serbia)" in Palaeogeography, Palaeoclimatology, Palaeoecology, Elsevier BV (2020). https://doi.org/10.1016/j.palaeo.2020.110145
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Pre-failure deformation monitoring as rockfall prediction tool
... Figure 4a reveals relatively large total 2013-2019 detachment, reaching a couple of cubic meters in volume, with mainly blocky material and eroded debris/talus. The largest X direction displacement is about 70 cm. In figure 5a, the profile line misses the most of the 2013-2014 event and reveals low ...
... cloud set, comprising of 7 point clouds (2013-2019). 4. Results and discussion The results will be presented sequentially, mimicking the data flow and monitoring activity. However, total observation period 2013-2019 will be used as the ultimate reference, together with between- sequence comparisons ...Miloš Marjanović, Biljana Abolmasov, Zoran Berisavljević, Marko Pejić, Petko Vranić. "Pre-failure deformation monitoring as rockfall prediction tool" in IOP Conference Series: Earth and Environmental Science, IOP Publishing (2021). https://doi.org/10.1088/1755-1315/833/1/012197
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A Mathematical Learning Environment Based on Serbian Language Resources
In recent years, in line with ever growing usage of Information technology, the learning environments are changing. The amount of available learning materials in various forms has increased. These new environments demand comprehensive learning systems, which enable management of the learning corpus with special attention paid to relevant lexical resources. In this paper we present the concept of a Mathematical Learning Environment in Serbian (MLES), which is based on a corpus of mathematical materials and various lexical resources, enabling ...... section Five offers the main features of the newly developed terminological resource, Termi. The paper end with some concluding remarks. 2. FLOW CONTROL The architecture of the MLES system is based on three main components. The first component is dedicated to corpus processing and alignment ...Radojičić Marija, Obradović Ivan, Stanković Ranka, Utvić Miloć, Kaplar Sebastijan. "A Mathematical Learning Environment Based on Serbian Language Resources" in Proceedings of the 7th International Scientific Conference Technics and Informatics in Education, Faculty of Technical Sciences, Čačak (2018)
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Fuzzy optimization in hydrodynamic analysis of groundwater control systems: Case study of the pumping station “Bezdan 1”, Serbia
Dragoljub Bajić, Dušan Polomčić (2014)A groundwater control system was designed to lower the water table and allow the pumping sta-tion “Bezdan 1” to be built. Based on a hydrodynamic analysis that suggested three alternative solutions, mul-ticriteria optimization was applied to select the best alternative. The fuzzy analytic hierarchy process methodwas used, based on triangular fuzzy numbers. An assessment of the various factors that influenced the selec-tion of the best alternative, as well as fuzzy optimization calculations, yielded the “weights” of the alternativesand the ...groundwater lowering, groundwater management scenario, fuzzy analytic hierarchy process,expert knowledge, triangular fuzzy numbers, linguistic variables... control system is comprised of 12 wells. It takes seven days to lower the water table to below the design elevation and establish quasi-steady groundwater flow. As pointed out in connection with the evaluation of crite- ria, in this alternative, if the canal stages should be DRAGOLJUB BAJIĆ & DUŠAN POLOMČIĆ108 ...Dragoljub Bajić, Dušan Polomčić. "Fuzzy optimization in hydrodynamic analysis of groundwater control systems: Case study of the pumping station “Bezdan 1”, Serbia" in Geološki anali Balkanskoga poluostrva, Belgrade : University of Belgrade - Faculty of mining and geology (2014). https://doi.org/10.2298/GABP1475103B
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Quantitative landslide risk assessment in the city of Tuzla
In the climate-changing conditions, geological environment interacts more dramatically with the urban fabric than before. The urbanization is expansive and more aggressive than before, but so are the weather extremes and long-term climate trends. In effect, many processes which can be triggered by either side, nature or engineering, are becoming more pervasive than before, and such is the case with landslides. Dealing and managing landslides requires few crucial steps, starting from collecting data on landslide location and typology – ...... 2013). Herein, it is attempted to complete the full scope from landslide inventorying to societal landslide risk quantification. Figure 1. Flow chart of the modeling procedure. The following sequence of techniques and procedures (Fig. 1) was implemented to that end ● Landslide inventorying: ...Miloš Marjanović, Biljana Abolmasov, Cvjetko Sandić, Miralem Mulać, Petar Begović. "Quantitative landslide risk assessment in the city of Tuzla" in SCG-Xiii International Symposium on Landslides. Cartagena, Colombia- February 22-26, 2021, International Society for Soil Mechanics and Geotechnical Engineering (2021)
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Control of substructure construction of railways in the Republic of Serbia
Контрола збијености природног тла (у ископу) или збијеног у насипу при изградњи саобраћајница представља један од основних облика контроле квалитета доњег строја. Код изградње брзих саобраћајница (аутопутеви и брза железница) приоритет је постизање високог нивоа контроле извршених радова. У циљу онемогућавања диференцијалног слегања (при изградњи насипа), или промене запремине услед допунског збијања материјала, које неминовно доводе до деформација, потребно је извршити оптимално збијање материјала. У оквиру овог рада приказује се техничка регулатива која регулише контролу збијености при изградњи железничке ...... Rc* where the ratio Ev2/ Ev1 less than the minimum value prescribed for Ev2. The protective layer as a filter must have water permeability, and the flow rate cannot be so high that the particles are washed away. To achieve this: the diameter of the grain belonging to the ordinate 15% of the granulometric ...Dragan Lukić, Dragoslav Rakić, Irena Basarić Ikodinović. "Control of substructure construction of railways in the Republic of Serbia" in International Conference On Contemporary Theory and Practice in Construction XV, Banja Luka 16-17 jun 2022., University of Banja Luka Faculty of Architecture, Civil Engineering and Geodesy (2022)
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Konceptualni model hidrogeotermalnog sistema šire okoline Brusa - geološki, geofizički i hidrogeološki uslovi / Conceptual model of hydrothermal system of Brus area - geological, geophysical and hydrogeological condition
Dejan Milenić, Ana Vranješ, Marinko Toljić, Ivana Vasiljević, Natalija Radosavljević, Matija Ognjanović (2024)Na širem području Brusa izvedena su naučna multidisciplinarna istraživanja za potrebe ocene geotermalnog potencijala sa zadatkom de9inisanja uslova formiranja geotermalnih i termomineralnih resursa. Interpretacijom podataka zaključeno je da je na predmetnom terenu formiran "hibridni" hidrogeotermalni sistem, koji sadrži elemente sistema u rov-strukturi i elemente konvektivnog hidrogeotermalnog sistema sa rezervoarom u pokrivaču granitoidne intruzije. Sistem čine dva nezavisna hidrogeotermalna rezervoara. Prvi rezervoar formiran je u gornjokrednim krečnjacima na dubini od oko 1550 m. Maksimalne prognozne temperature hidrogeotermalnih resursa u krečnjačkom ...Dejan Milenić, Ana Vranješ, Marinko Toljić, Ivana Vasiljević, Natalija Radosavljević, Matija Ognjanović. "Konceptualni model hidrogeotermalnog sistema šire okoline Brusa - geološki, geofizički i hidrogeološki uslovi / Conceptual model of hydrothermal system of Brus area - geological, geophysical and hydrogeological condition" in XVII Srpski simpozijum o hidrologiji sa međunarodnim učešćem , Pirot, Srbija, 02-06. October 2024, Beograd : Univerzitet u Beogradu - Rudarsko-geološki fakultet (2024). https://doi.org/10.5281/zenodo.13739406
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Dehydroicetexanes in sediments and crude oils: Possible markers for Cupressoideae
Hans Peter Nytoft, Geir Kildahl-Andersen, Sofie Lindström, Frode Rise, Achim Bechtel, Danica Mitrović, Nataša Đoković, Dragana Životić, Ksenija A. Stojanović (2019)Two previously unidentified dehydroabietane isomers were isolated from Miocene Serbian lignite and Rhaetian (Late Triassic) coaly mudstones from South Sweden and characterized using NMRspectroscopy as cis- and trans-dehydroicetexane. Both have a 9(10?20)-abeo-abietane or icetexane skeleton, consisting of a 6-7-6 tricyclic framework with seven carbons in ring B instead of the usual six in common diterpanes of the abietane-type. Dehydroicetexanes can be detected using GC-MS-MS in m/z 270?146 chromatograms without interference from dehydroabietane or other isomers. Dehydroicetexanes are often abundant ...Hans Peter Nytoft, Geir Kildahl-Andersen, Sofie Lindström, Frode Rise, Achim Bechtel, Danica Mitrović, Nataša Đoković, Dragana Životić, Ksenija A. Stojanović. "Dehydroicetexanes in sediments and crude oils: Possible markers for Cupressoideae" in Organic Geochemistry, Elsevier BV (2019). https://doi.org/10.1016/j.orggeochem.2019.01.001
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Differently shaped nanocrystalline (Fe, Y)3O4 and its adsorption efficiency toward inorganic arsenic species
Biljana P Dojčinović, Boštjan Jančar, Lotfi Bessais, Aleksandar Kremenović, Nataša P Jović-Jovičić, Predrag T Banković, Dalibor M Stanković, Miloš Ognjanović, Bratislav V Antić (2019)Herein we report effects of partial substitution of Fe3+ by Y3+ in magnetite (Fe3O4) on morphology and inorganic arsenic species adsorption efficiency of the Fe3−xYxO4 nanoparticles formed. The series of Fe3−xYxO4 (x=0.00, 0.042 and 0.084, labeled as Y00, Y05 and Y10, respectively) was synthesized using co-precipitation followed by microwave-hydrothermal treatment (MW) at 200°C. With increase of yttrium content(xvalue), both the morphological inhomogeneity of the samples and the fraction of spinel nanorods as compared to spinel pseudospherical particles increased. By ...Biljana P Dojčinović, Boštjan Jančar, Lotfi Bessais, Aleksandar Kremenović, Nataša P Jović-Jovičić, Predrag T Banković, Dalibor M Stanković, Miloš Ognjanović, Bratislav V Antić. "Differently shaped nanocrystalline (Fe, Y)3O4 and its adsorption efficiency toward inorganic arsenic species" in Nanotechnology, IOP Publishing (2019). https://doi.org/10.1088/1361-6528/ab3ca2