Претрага
553 items
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Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands
Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski (2023)Cancer remains one of the world's deadliest diseases, claiming many lives each day. Transition metal complexes are leading candidates in developing anticancer agens with cisplatin used in chemotherapy worldwide. Copper, an endogenous metal in the human body, is especially attractive because of its typical redox biological activities and a relatively strong affinity to nucleobases. A series of Cu(II) complexes with ethane-1,2-diamine as the amine part and pentane-2,4-dione and/or 1-phenylbutane-1,3-dione, pentane-2,4-dione and/or 1,1,1- trifluoropentane-2,4-dione, or 1,1,1-trifluoropentane-2,4-dione and/or 1-phenylbutane-1,3-dione as the ...Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski. "Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands" in Applied Organometallic Chemistry, Wiley (2023). https://doi.org/10.1002/aoc.7253
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Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
Lena Platanić Arizanović, Nikola Gligorijević, Ilija Cvijetić, Aleksandar Mijatović, Maja Krstić Ristivojević, Simeon Minić, Aleksandra Nikolić Kokić, Čedo Miljević, Milan Nikolić (2023)Packed with hemoglobin, an essential protein for oxygen transport, human erythrocytes are a suitable model system for testing the pleiotropic effects of lipophilic drugs. Our study investi gated the interaction between antipsychotic drugs clozapine, ziprasidone, sertindole, and human hemoglobin under simulated physiological conditions. Analysis of protein fluorescence quenching at different temperatures and data obtained from the van’t Hoff diagram and molecular docking indicate that the interactions are static and that the tetrameric human hemoglobin has one binding site for ...Inorganic Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Computer Science Applications, Spectroscopy, Molecular Biology, General Medicine, CatalysisLena Platanić Arizanović, Nikola Gligorijević, Ilija Cvijetić, Aleksandar Mijatović, Maja Krstić Ristivojević, Simeon Minić, Aleksandra Nikolić Kokić, Čedo Miljević, Milan Nikolić. "Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?" in International Journal of Molecular Sciences, MDPI AG (2023). https://doi.org/10.3390/ijms24108921
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Crystallographic, spectroscopic, thermal and computational studies of polymeric cobalt(II)–mellitate complex with 2,2′-bipyridine
Orange single crystals of new polymeric cobalt(II) complex {[Co(bipy)(H2O)4]2[Co(μ-mell)(H2O)2]·10H2O}n, 1, were synthesized by slow evaporation method at room temperature (bipy = 2,2′-bipyridine, mell = hexaanion of mellitic acid) and its crystal structure was determined by single-crystal X-ray diffraction. The complex 1 was characterized based on elemental analysis, FTIR spectroscopy and thermal (TG/DTA) analysis followed by computational analysis of noncovalent interactions and quantum chemical calculations of interaction energies. In 1, two crystallographically different Co(II) atoms adopt a deformed octahedral geometry, ...Lidija Radovanović, Dušan P. Malenov, Marko V. Rodić, Aleksandar Kremenović, Jelena Rogan. "Crystallographic, spectroscopic, thermal and computational studies of polymeric cobalt(II)–mellitate complex with 2,2′-bipyridine" in Journal of Molecular Structure, Elsevier BV (2021). https://doi.org/10.1016/j.molstruc.2021.132202
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In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge
Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić (2023)The biological activity of six structurally similar tetradentate Schiff base copper(II) complexes, namely [Cu(ethylenediamine-bis-acetylacetonate)] (CuAA) and five derivatives where two methyl groups are replaced by phenyl, (CuPP), CF3 (CuTT) or by mixed groups CH3/CF3 (CuAT), Ph/CF3 (CuPT), and Ph/CH3 (CuAP) has been investigated. The set of antioxidant assays was performed, and the results were expressed as IC50 and EC50 values. The series of complexes showed interesting bioactivity and were investigated for the determination of antioxidant, antifungal, antimicrobial, and cytotoxic ...Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić. "In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112224
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In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge
Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić (2023)The biological activity of six structurally similar tetradentate Schiff base copper(II) complexes, namely [Cu (ethylenediamine-bis-acetylacetonate)] (CuAA) and five derivatives where two methyl groups are replaced by phenyl, (CuPP), CF3 (CuTT) or by mixed groups CH3/CF3 (CuAT), Ph/CF3 (CuPT), and Ph/CH3 (CuAP) has been investigated. The set of antioxidant assays was performed, and the results were expressed as IC50 and EC50 values. The series of complexes showed interesting bioactivity and were investigated for the determination of antioxidant, antifungal, antimicrobial, and ...Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić. "In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112224
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Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes
Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović (2023)In order to discover new anticancer drugs, novel ruthenium(III) complexes [Ru(L)Cl(H2O)], where L is tetradentate Schiff base bis(acetylacetone)ethylendiimine (acacen, 1), bis(benzoylacetone)ethylendiimine (bzacen, 2), (acetylacetone)(benzoylaceton)ethylendiimine (acacbzacen, 3), bis(acetylacetone)propylendiimine (acacpn, 4), bis(benzoylacetone)propylendiimine (bzacpn, 5) or (acetylacetone)(benzoylaceton)propylendiimine (acacbzacpn, 6), were synthesized. The complexes 1 – 6 were characterized by elemental analysis, molar conductometry, and by various spectroscopic techniques, such as UV–Vis, IR, EPR, and ESI-MS. Based on in vitro DNA/BSA experiments, complexes 2 (bzacen) and 5 (bzacpn) with two aromatic rings showed ...Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović. "Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112363
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Influence of mono- and two-component organic modifiers on determination of lipophilicity of tetradentate Schiff bases
The infuences of the application of mono- and two-component organic modifers on lipophilicity determination of 12 tetradentate Schif bases by reversed-phase thin layer chromatography were investigated. The main goal is to estimate types of interaction between observed compounds and components of the applied chromatographic systems and establish some behaviour pattern in order to easier choose a combination of organic modifers which will simulate interaction in biological systems based on the facts that the same basic intermolecular interactions are responsible ...Materials Chemistry, Industrial and Manufacturing Engineering, General Chemical Engineering, Biochemistry,General ChemistryNikola Stevanović, Aleksandar Mijatović, Aleksandar Lolić, Mario Zlatović, Rada Baošić. "Influence of mono- and two-component organic modifiers on determination of lipophilicity of tetradentate Schiff bases" in Chemical Papers, Springer Science and Business Media LLC (2021). https://doi.org/10.1007/s11696-021-01884-5
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Influence of mono- and two-component organic modifiers on determination of lipophilicity of tetradentate Schiff bases
The infuences of the application of mono- and two-component organic modifers on lipophilicity determination of 12 tet radentate Schif bases by reversed-phase thin layer chromatography were investigated. The main goal is to estimate types of interaction between observed compounds and components of the applied chromatographic systems and establish some behaviour pattern in order to easier choose a combination of organic modifers which will simulate interaction in biological systems based on the facts that the same basic intermolecular interactions are ...Materials Chemistry, Industrial and Manufacturing Engineering, General Chemical Engineering, Biochemistry, General ChemistryNikola Stevanović, Aleksandar Mijatović, Aleksandar Lolić, Mario Zlatović, Rada Baošić. "Influence of mono- and two-component organic modifiers on determination of lipophilicity of tetradentate Schiff bases" in Chemical Papers, Springer Science and Business Media LLC (2021). https://doi.org/10.1007/s11696-021-01884-5
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An efficient class of optimal sixteenth-order root-finding methods and their basins of attraction
Dejan Ćebić, Nebojša M. Ralević (2022)Dejan Ćebić, Nebojša M. Ralević. "An efficient class of optimal sixteenth-order root-finding methods and their basins of attraction" in Journal of Mathematical Chemistry, Springer Science and Business Media LLC (2022). https://doi.org/10.1007/s10910-022-01371-6
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NMR kinetic studies of the interactions between [Ru(terpy)(bipy)(H2O)]2+ and some sulfur-donor ligands
Aleksandar Mijatović, Biljana Šmit, Ana Rilak, Biljana Petrović, Dragan Čanović, Živadin D. Bugarčić (2012)Reakcije supstitucije monofunkcionalnog [Ru(terpi)(bipi)(H2O)]2+ kompleksa, gde je terpi = 2,2′:6′,2″-terpiridin i bipi = 2,2′-bipiridin, sa biološki relevantnim sumporo donorskim ligandima, kao što su tiourea, l-metionin, l-cistein i glutation, proučavane su u vodenim rastvorima tehnikom 1H i 13C NMR spektroskopije. Sve reakcije su proučavajne na pH 7,4, u prisustvu fosfatnog pufera, da bi se oponašalo fiziološko okruženje tokom procesa supstitucije. Reakcije se izvode na 295 K pod uslovima reakcija drugog reda. Uočeni rezultati pokazuju da brzina supstitucije snažno zavisi ...Aleksandar Mijatović, Biljana Šmit, Ana Rilak, Biljana Petrović, Dragan Čanović, Živadin D. Bugarčić. "NMR kinetic studies of the interactions between [Ru(terpy)(bipy)(H2O)]2+ and some sulfur-donor ligands" in Inorganica Chimica Acta, Elsevier BV (2012). https://doi.org/10.1016/j.ica.2012.09.016
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Effects of production conditions on the properties of limestone briquettes aimed for acid soil liming
Vladimir Jovanović, Dragana Nišić, Vladimir Milisavljević, Dejan Todorović, Dragan Radulović, Branislav Ivošević, Sonja Milićević (2022)Vladimir Jovanović, Dragana Nišić, Vladimir Milisavljević, Dejan Todorović, Dragan Radulović, Branislav Ivošević, Sonja Milićević . "Effects of production conditions on the properties of limestone briquettes aimed for acid soil liming" in Chemical Industry (2022). https://doi.org/10.2298/HEMIND220211011J
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Development and Validation of Universal 3D Blast Fragmentation Model
Fluid Flow and Transfer Processes, Computer Science Applications,Process Chemistry and Technology, General Engineering, Instrumentation, General Materials ScienceVeljko Lapčević, Slavko Torbica, Miloš Stojanović, Ivica Vojinović. "Development and Validation of Universal 3D Blast Fragmentation Model" in Applied Sciences, MDPI AG (2023). https://doi.org/10.3390/app13148316
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Hydrogeochemical approach to estimate the quality of bottled waters in Serbia
Marina Ćuk, Maja Todorović, Jovana Šisović, Jana Štrbački, Jakov Andrijašević, Petar Papić. "Hydrogeochemical approach to estimate the quality of bottled waters in Serbia" in Chemical Industry, National Library of Serbia (2015). https://doi.org/10.2298/HEMIND150325042C
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Crystal-chemistry of the alkaline-earth hydrogen arsenates: crystal structure and vibrational spectraof a new Ba(AsO3OH) polymorphic variety
Đorđević Tamara, Karanović Ljiljana (2010)Đorđević Tamara, Karanović Ljiljana. "Crystal-chemistry of the alkaline-earth hydrogen arsenates: crystal structure and vibrational spectraof a new Ba(AsO3OH) polymorphic variety" in Book of Abstracts, XI General Meeting of the Russian Mineralogical Society combined with Fedorov Session, St. Petersburg, Russia: (2010): 88-89
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Organoselenium functionalized oxacycles as ligands in some trans-palladium(II) complexes: biological evaluation and interaction with small biomolecules
I. Raković, D. Ćoćić, O. Milošević-Djordjević, I. Radojević, M. N. Živanović, K. Virijević, J. Pavić, J. Tubić Vukajlović, A. Marković, J. S. Marjanović, M. D. Kostić, P. Čanović, A. Mijatović, V. M. Divac (2023)In this article, the biological evaluation and interaction of three selenium-based trans-palladium complexes (Pd–Se1, Pd–Se2, and Pd–Se3) with small biomolecules were performed. The UV–Vis kinetic studies on substitution reaction of synthesized complexes with selected biologically important N- and S-bonding ligands (LCys, GSH, L-Met, 50-GMP, L-His) has emphasized greater affinity of sulphur-based ligands for complex-binding, while the general order of the reactivity was L-Cys > GSH > L-Met > 50-GMP > L-His. The complex reactivity toward small biomolecules is influenced ...I. Raković, D. Ćoćić, O. Milošević-Djordjević, I. Radojević, M. N. Živanović, K. Virijević, J. Pavić, J. Tubić Vukajlović, A. Marković, J. S. Marjanović, M. D. Kostić, P. Čanović, A. Mijatović, V. M. Divac. "Organoselenium functionalized oxacycles as ligands in some trans-palladium(II) complexes: biological evaluation and interaction with small biomolecules" in Journal of Coordination Chemistry, Informa UK Limited (2023). https://doi.org/10.1080/00958972.2023.2256934
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Novel cerium and praseodymium doped phosphate tungsten bronzes: Synthesis, characterization, the behavior in the Briggs-Rauscher reaction and photoluminescence properties
Tijana Maksimović, Pavle Tančić, Jelena Maksimović, Dimitrije Mara, Marija Ilić, Rik Van Deun, Ljubinka Joksović, Maja Pagnacco (2023)Due to the interesting and potentially useful properties, phosphate tungsten bronzes are constantly being studied and attract a lot of attention. In the present work, two different metallic elements, belonging to the group of rare-earth metals, cerium and praseodymium, were used as a dopants for phosphate tungsten bronzes. Novel cerium and praseodymium doped phosphate tungsten bronzes were successfully synthesized and further characterized by thermal analyses, Fourier-transform infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy with energy-dispersive X-ray spectrometer and ...Electrical and Electronic Engineering, Atomic and Molecular Physics and Optics, Electronic, Optical and Magnetic Materials, Inorganic Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, SpectroscopyTijana Maksimović, Pavle Tančić, Jelena Maksimović, Dimitrije Mara, Marija Ilić, Rik Van Deun, Ljubinka Joksović, Maja Pagnacco. "Novel cerium and praseodymium doped phosphate tungsten bronzes: Synthesis, characterization, the behavior in the Briggs-Rauscher reaction and photoluminescence properties" in Optical Materials, Elsevier BV (2023). https://doi.org/10.1016/j.optmat.2023.114125
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Crystallography and Surface Oxidation of Stoichiometric Arsenopyrite from Šumadija-Kopaonik Pb-Zn/Polymetallic Ore District (Serbia)
Ivana Jelić, Aleksandar Pačevski, Aleksandar Kremenović, Aleš Šoster, Andreja Šestan, Janez Zavašnik (2023)The behaviour and stability of arsenopyrite largely depend on its crystal structure, but studies of crystallography and structural defects are scarce. For clarification, we investigated a series of natural arsenopyrite crystals from the polymetallic Pb-Zn-(±Cu,Ag,Au,Sb,Bi,W) Šumadija-Kopaonik ore district (Serbia) by powder X-ray diffraction (XRPD). Among them, samples from the Drenjak gold mineralisation showed near-stoichiometric FeAsS composition and were further investigated by conventional and high-resolution transmission electron microscopy methods. TEM revealed abundant planar crystallographic defects and epitaxial surface oxide layer ...Inorganic Chemistry, Condensed Matter Physics,General Materials Science, General Chemical Engineering, crystal structure, FeAsS, oxidation, TEM, XRPD... potential ecological concerns due to As release through sulphide weathering and oxidation. The existing, research on arsenopyrite mainly focuses on the chemistry, processing, and weathering of the Au-containing arsenic sulphide minerals [4]. The ability to incorporate Au in FeAsS structure coincides with ...
... arsenopyrite crystal structure. Conflicts of Interest: The authors declare no conflict of interest. References 1. · Vaughan, D.J.;Craig, J. Mineral Chemistry of Metal Sulfides; Cambridgjee University Press: Cambridge, UK, 1978. 2. · Merkulova, M.; Mathon, O.; Glatzel, P.; Rovezzi, M.; Batanova, V.; Marion ...Ivana Jelić, Aleksandar Pačevski, Aleksandar Kremenović, Aleš Šoster, Andreja Šestan, Janez Zavašnik. "Crystallography and Surface Oxidation of Stoichiometric Arsenopyrite from Šumadija-Kopaonik Pb-Zn/Polymetallic Ore District (Serbia)" in Crystals, MDPI AG (2023). https://doi.org/10.3390/cryst13020278
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DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O Schiff base copper(II) complexes
Aleksandar Mijatović, Angelina Caković, Aleksandar Lolić, Snezana Sretenović, Marko Živanović, Dragana Seklić, Jovana Bogojeski, Biljana Petrović (2023)Three Schiff base Cu(II) complexes, (N,N’-bis(acetylacetone)propylenediimine)copper(II) complex, [Cu(acac2pn)] (1), (N,N'-bis-(benzoylacetone)propylenediimine)copper(II) complex, [Cu(phacac2pn)] (2) and (N,N’-bis-(trifluoroacetylacetone)propylenediimine)copper(II) complex, [Cu(tfacac2pn)] (3), were used to investigate the interactions with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) using the electronic absorption and spectroscopic fluorescence methods. UV-Vis absorption studies showed that studied complexes interact with DNA molecule and exhibit moderate binding affinity. Fluorescence studies of complexes 1-3 also showed a possibility for DNA intercalation as well as a relatively high binding ability ...Aleksandar Mijatović, Angelina Caković, Aleksandar Lolić, Snezana Sretenović, Marko Živanović, Dragana Seklić, Jovana Bogojeski, Biljana Petrović. "DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O Schiff base copper(II) complexes" in Journal of the Serbian Chemical Society (2023). https://doi.org/10.2298/JSC230614063M
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Substitution reactions of some novel sterically hindered monofunctional Pd(II) complexes
Reakcije supstitucije monofunkcionalnih kompleksa [(TLtBu)PdCl]+ i [Pd(tpdm)Cl]+, gde je TLtBu = 2,6-bis[(1,3-di-terc-butilimidazolin-2-imino)metil]piridin i tpdm = terpiridindimetan, sa nukleofilima kao što su: tiourea, I−, Br−, NO2−, piridin i dimetil-sulfoksid (DMSO) proučavani su u 0,1 M vodenom rastvoru NaClO4 u prisustvu 10 mM NaCl. Reakcije su sprovedene na tri različite temperature (288, 298 i 308 K) korišćenjem tehnike zaustavljenog protoka na različitim temperaturama. Reakcije supstitucije su praćene pod uslovima pseudo prvog reda sa velikim viškom nukleofila. Dobijeni rezultati pokazuju da kompleks ...... W.B. Tolman, M. Tamm, Dalton Trans. (2008) 887. [27] T.G. Appleton, J.R. Hall, S.F. Ralph, C.S.M. Thompson, Inorg. Chem. 23 (1984) 3521. [28] Inorganic Reaction Mechanisms, in: M.L. Tobe and J. Burgess (Ed.), Addison Wesley Longman Inc., Essex, 1999, p. 74. [29] P. Illner, S. Kern, S. Begel, R. van ...Aleksandar Mijatović, Jovana Bogojeski, Biljana Petrović, Živadin D. Bugarčić. "Substitution reactions of some novel sterically hindered monofunctional Pd(II) complexes" in Inorganica Chimica Acta, Elsevier BV (2011). https://doi.org/10.1016/j.ica.2011.11.031
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Spatial–temporal assessment of hydrocarbon biodegradation mechanisms at a contaminated groundwater site in Serbia
Nenad Marić, Jana Štrbački, Jason Polk, Latinka Slavković Beškoski, Jelena Avdalović, Marija Lješević, Kristina Joksimović, Aleksandra Žerađanin, Vladimir P. Beškoski (2022)General Earth and Planetary Sciences,General Environmental Science,Ecology,Ecology, Evolution, Behavior and SystematicsNenad Marić, Jana Štrbački, Jason Polk, Latinka Slavković Beškoski, Jelena Avdalović, Marija Lješević, Kristina Joksimović, Aleksandra Žerađanin, Vladimir P. Beškoski. "Spatial–temporal assessment of hydrocarbon biodegradation mechanisms at a contaminated groundwater site in Serbia" in Chemistry and Ecology, Informa UK Limited (2022). https://doi.org/10.1080/02757540.2021.2017903